{"orpha":95626,"name":"Acquired arginine vasopressin deficiency","type":"Clinical subtype","group":"Subtype of disorder","status":"active","flags":[],"synonyms":["Acquired CDI","Acquired neurogenic diabetes insipidus"],"definition":"A subtype of central diabetes insipidus (CDI) characterized by polyuria and polydipsia, due to an idiopathic or secondary decrease in vasopressin (AVP) production.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-95626/","orphanet_url":"https://www.orpha.net/en/disease/detail/95626","names":{"fr":{"name":"Déficit acquis en arginine vasopressine","synonyms":["DIC acquis","Diabète insipide neurogène acquis"],"definition":"Le diabète insipide central acquis (DIC acquis) est un sous-type de diabète insipide central (DIC) caractérisé par une polyurie et une polydipsie, due à une diminution de la production de vasopressine de cause idiopathique ou secondaire."},"de":{"name":"Arginin-Vasopressin-Mangel, erworbener","synonyms":["CDI, erworbener","Neurogener Diabetes insipidus, erworbener"],"definition":"Der Erworbene zentrale Diabetes insipidus (erworbener CDI) ist ein Subtyp des Zentralen Diabetes insipidus (CDI; s. dort) und gekennzeichnet durch Polyurie und Polydipsie als Folge einer idiopathischen oder sekundären Verminderung der Produktion von Vasopressin (AVP)."},"es":{"name":"Deficiencia de arginina vasopresina adquirida","synonyms":["DIC adquirida","Diabetes insipida central adquirida","Diabetes insipida neurogénica adquirida"],"definition":"Es un subtipo de diabetes insípida central (DIC) caracterizado por poliuria y polidipsia debido a una disminución idiopática o secundaria en la producción de vasopresina (AVP)."},"it":{"name":"Deficit acquisito di arginina vasopressina","synonyms":["CDI acquisito","Diabete insipido neurogeno acquisito"],"definition":"Il diabete insipido acquisito (CDI acquisito) è un sottotipo del diabete insipido centrale (CDI; si veda questo termine), caratterizzato da poliuria e polidipsia; è causato dalla riduzione idiopatica o secondaria della produzione di vasopressina (AVP)."},"nl":{"name":"Verworven deficiëntie van arginine-vasopressine","synonyms":["Verworven neurogene diabetes insipidus","Verworven CDI"],"definition":"Een subtype van centrale diabetes insipidus (CDI), gekarakteriseerd door polyurie en polydipsie als gevolg van een idiopathische of secundaire daling van de productie van vasopressine (AVP)."},"pt":{"name":"Deficiência de arginina vasopressina adquirida","synonyms":["CDI adquirida","Diabetes insipidus neurogénica adquirida"],"definition":"A diabetes insípida central adquirida (CDI adquirida) é um subtipo de diabetes insípida central (CDI, ver este termo), caracterizada por poliúria e polidipsia, devido a uma diminuição idiopática ou secundária na produção de vasopressina (AVP)."},"pl":{"name":"Nabyta moczówka prosta centralna","synonyms":["Nabyta CDI","Nabyta moczówka prosta neurogenna","Nabyty niedobór wazopresyny argininowej"]},"cs":{"name":"Ziskaný centrální diabetes insipidus","synonyms":["Získaný CDI","Získaný neurogenní diabetes insipidus"]},"uk":{"name":"Набутий дефіцит аргінін-вазопресину","synonyms":["Набутий CDI","Набутий нейрогенний нецукровий діабет"],"definition":"A subtype of central diabetes insipidus (CDI) characterized by polyuria and polydipsia, due to an idiopathic or secondary decrease in vasopressin (AVP) production."},"zh":{"name":"获得性中枢性尿崩症","synonyms":["获得性神经性尿崩症"],"definition":"中枢性尿崩症的一种亚型，以血管加压素（AVP）生成特发性或继发性减少所致多尿和多饮为特征。"},"tr":{"name":"Edinsel santral diabetes insipidus","synonyms":["Edinsel CDI","Edinsel nörojenik diabetes insipidus"]}},"xrefs":[{"source":"ICD-10","code":"E23.2","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"5A61.5","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1677009817"},{"source":"MONDO","code":"0019846","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5680256","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[{"type":"Referred to","orpha":95625,"name":"OBSOLETE: Posttraumatic diabetes insipidus","status":"inactive"}],"preferential_parent":{"orpha":97978,"name":"Rare endocrine disease"},"parents":[{"orpha":178029,"name":"Arginine vasopressin deficiency","classifications":[193]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2016-06-01","source":null,"terms":[{"hpo":"HP:0000873","label":"Diabetes insipidus","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0100515","label":"Pollakisuria","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001959","label":"Polydipsia","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001824","label":"Weight loss","frequency":"Frequent (79-30%)","criteria":null}]}}