{"orpha":95491,"name":"Congenital coronary artery aneurysm","type":"Morphological anomaly","group":"Disorder","status":"active","flags":[],"synonyms":["Congenital coronary aneurysm"],"definition":"Congenital coronary artery aneurysm is a rare congenital coronary artery malformation defined as a more than 1.5 fold the normal size dilatation of a coronary artery segment with no identified underlying inflammatory or connective tissue disease. It may be asymptomatic or may present with angina pectoris, myocardial infarction, sudden cardiac death, fistula formation, pericardial tamponade, compression of surrounding structures, or congestive heart failure.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-95491/","orphanet_url":"https://www.orpha.net/en/disease/detail/95491","names":{"fr":{"name":"Anévrisme congénital des artères coronaires","definition":"Une malformation congénitale rare des artères coronaires. Elle est définie par une dilatation du segment de l'artère coronaire de plus de 1,5 fois, en l'absence d'une maladie inflammatoire ou d'une affection du tissu conjonctif sous-jacente. Elle peut être asymptomatique ou se manifester par une angine de poitrine, un infarctus du myocarde, un décès subit d'origine cardiaque, la formation d'une fistule, une tamponnade péricardique, une compression des structures environnantes ou une insuffisance cardiaque congestive."},"de":{"name":"Koronararterienaneurysma, kongenitales","synonyms":["Koronaraneurysma, kongenitales"],"definition":"Das kongenitale Koronararterienaneurysma ist eine seltene angeborene Koronararterienfehlbildung, die als eine mehr als 1,5-fache Erweiterung eines Koronararteriensegments ohne nachgewiesene entzündliche oder bindegewebige Grunderkrankung definiert ist. Sie kann asymptomatisch sein oder sich mit Angina pectoris, Myokardinfarkt, plötzlichem Herztod, Fistelbildung, Perikardtamponade, Kompression umliegender Strukturen oder kongestiver Herzinsuffizienz präsentieren."},"es":{"name":"Aneurisma congénito de la arteria coronaria","synonyms":["Aneurisma coronario congénito"],"definition":"El aneurisma congénito de la arteria coronaria, es una malformación congénita poco frecuente de la arteria coronaria definida como una dilatación superior a 1,5 veces el tamaño normal de un segmento de arteria coronaria sin enfermedad inflamatoria o del tejido conectivo subyacente identificada. Puede ser asintomático o presentarse con angina de pecho, infarto de miocardio, muerte súbita cardíaca, formación de fístulas, taponamiento pericárdico, compresión de las estructuras circundantes o insuficiencia cardíaca congestiva."},"it":{"name":"Aneurisma congenito dell'arteria coronaria","definition":"L'aneurisma congenito dell'arteria coronaria è una malformazione congenita rara caratterizzata dalla dilatazione di un segmento dell'arteria coronaria, che risulta 1,5 volte più grande del normale, in assenza di evidenti malattie infiammatorie o del tessuto connettivo. I pazienti possono essere asintomatici, oppure presentare angina pectoris, infarto del miocardio, morte cardiaca improvvisa, formazione di una fistola, tamponamento pericardico, compressione delle strutture circostanti o insufficienza cardiaca congestizia."},"nl":{"name":"Congenitaal aneurysma van coronaire arteriën","synonyms":["Congenitaal aneurysma van kransslagaders","Congenitaal coronair aneurysma"],"definition":"Congenitaal aneurysma van coronaire arteriën is een zeldzame congenitale malformatie van de kransslagaders die gedefinieerd wordt als een dilatatie van meer dan 1,5 keer de normale omvang van een segment van een kransslagader zonder een geïdentificeerde onderliggende inflammatoire ziekte of bindweefselziekte. Het kan asymptomatisch zijn of zich voordoen met angina pectoris, hartinfarct, plotse hartdood, vorming van een fistel, harttamponade, compressie van omliggende structuren, of congestief hartfalen."},"pt":{"name":"Aneurisma da artéria coronária, congénito"},"pl":{"name":"Wrodzony tętniak tętnicy wieńcowej","synonyms":["Congenital coronary aneurysm"]},"cs":{"name":"Vrozené aneuryzma koronární tepny","synonyms":["Congenital coronary aneurysm"]},"uk":{"name":"Вроджена аневризма коронарних артерій","synonyms":["Вроджена аневризма коронарних судин"],"definition":"Congenital coronary artery aneurysm is a rare congenital coronary artery malformation defined as a more than 1.5 fold the normal size dilatation of a coronary artery segment with no identified underlying inflammatory or connective tissue disease. It may be asymptomatic or may present with angina pectoris, myocardial infarction, sudden cardiac death, fistula formation, pericardial tamponade, compression of surrounding structures, or congestive heart failure."},"zh":{"name":"先天性冠状动脉瘤","synonyms":["先天性冠状动脉瘤"],"definition":"先天性冠状动脉瘤是一种罕见的先天性冠状动脉畸形，其定义为一个冠状动脉节段在无炎症或结缔组织疾病的情况下，扩张为正常大小的1.5倍以上。该病可能无症状，也可能表现为心绞痛、心肌梗死、心源性猝死、瘘管形成、心包填塞、周围结构受压或充血性心力衰竭。"},"tr":{"name":"Doğumsal koroner arter anevrizması","synonyms":["Doğumsal koroner anevrizma"]}},"xrefs":[{"source":"ICD-10","code":"Q24.5","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"LA8C.Y","qualifier":"BTNT","icd_relation":"index","validated":true,"icd11_uri":"1376805686"},{"source":"MONDO","code":"0019825","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0340627","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":1081,"name":"Coronary artery congenital malformation","classifications":[147,148]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}