{"orpha":93940,"name":"Laryngotracheoesophageal cleft type 3","type":"Clinical subtype","group":"Subtype of disorder","status":"active","flags":[],"synonyms":["LTEC III","LTEC3","Laryngo-tracheo-esophageal cleft type 3"],"definition":"A congenital respiratory tract anomaly characterized by a cleft extending through the cricoid cartilage, sometimes into the cervical trachea, with severe swallowing disorders, lung infections and pulmonary damage.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-93940/","orphanet_url":"https://www.orpha.net/en/disease/detail/93940","names":{"fr":{"name":"Fente laryngo-trachéo-oesophagienne type 3","synonyms":["LTEC III","LTEC3"],"definition":"La fente laryngo-trachéo-oesophagienne (FLTO) de type 3 est une malformation congénitale de l'appareil respiratoire caractérisée par une fente se prolongeant en dessous des cordes vocales à travers le cartilage cricoïde, parfois jusqu'à la trachée cervicale ; elle s'accompagne de troubles sévères de la déglutition avec infections et lésions pulmonaires."},"de":{"name":"Laryngo-tracheo-ösophageale Spalte Typ 3","synonyms":["LTEC III","LTEC3"],"definition":"Die Laryngo-tracheo-ösophageale Spalte (LC) Typ 3 ist eine angeborene Fehlbildung der Atemwege und gekennzeichnet durch eine Spalte, die sich durch den Kehlkopfknorpel hindurch und manchmal bis in den Halsteil der Trachea ausdehnt. Die Fehlbildung ist verbunden mit schweren Schluckstörungen, Lungeninfektionen und Lungenschaden."},"es":{"name":"Hendidura laringotraqueoesofágica tipo 3","synonyms":["Hendidura laringo-traqueo-esofágica tipo 3","LTEC III","LTEC3"],"definition":"Es una anomalía congénita del tracto respiratorio caracterizada por una hendidura que se extiende a través del cartílago cricoides, a veces dentro de la tráquea cervical, con trastornos al tragar graves, infecciones en el pulmón y daños pulmonares."},"it":{"name":"Schisi laringo-tracheo-esofagea, tipo 3","synonyms":["LTEC III","LTEC3"],"definition":"La schisi laringo-tracheo-esofagea (LC) tipo 3 è un difetto congenito delle vie respiratorie, caratterizzato da una schisi che si estende lungo la cartilagine cricoide, a volte a livello della trachea cervicale, che comporta gravi disturbi della deglutizione, infezioni e danno polmonare."},"nl":{"name":"Laryngo-tracheo-oesofageale fissuur type 3","synonyms":["LTEC III","LTEC3"],"definition":"Een congenitale anomalie van luchtwegen, gekenmerkt door een spleet die zich uitstrekt door het cricoïd (ringkraakbeen), soms tot in de cervicale luchtpijp, met ernstige slikstoornissen, longinfecties en longschade."},"pt":{"name":"Fenda laringotraqueoesofágica tipo 3","definition":"A fenda laringo-tráqueo-esofágica (LC) tipo 3 é uma anomalia congénita do trato respiratório caracterizada por uma fenda que se estende através da cartilagem cricóide, às vezes chegando a atingir a traqueia cervical, com graves perturbações da deglutição, infeções e danos pulmonares."},"pl":{"name":"Rozszczep krtaniowo-tchawiczo-przełykowy typu 3","synonyms":["LTEC3","LTEC III"]},"cs":{"name":"Laryngotracheoezofageální rozštěp, typ 3","synonyms":["LTEC III","LTEC3"]},"uk":{"name":"Ларинготрахеостравохідна розщілина, тип 3","synonyms":["Ларинго-трахео-стравохідна щілина 3 типу","LTEC III","LTEC3"],"definition":"A congenital respiratory tract anomaly characterized by a cleft extending through the cricoid cartilage, sometimes into the cervical trachea, with severe swallowing disorders, lung infections and pulmonary damage."},"zh":{"name":"喉气管食管裂3型","synonyms":["喉-气管-食管裂3型"],"definition":"一种先天性呼吸道畸形，其特征是裂隙延伸过环状软骨，有时累及颈部气管，伴有严重的吞咽障碍、肺部感染和肺损伤。"},"tr":{"name":"Laringotrakeoözofageal yarık tip 3","synonyms":["LTEC3","LTEC III","Laringo-trakeo-özofageal yarık tip 3"]}},"xrefs":[{"source":"OMIM","code":"215800","qualifier":"BTNT","icd_relation":null,"validated":true},{"source":"ICD-10","code":"Q32.1","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"LA72","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1369602668"},{"source":"MONDO","code":"0019763","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0584825","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":2004,"name":"Laryngotracheoesophageal cleft","classifications":[147,156,182,184,186,200]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["Infancy","Neonatal"],"prevalence":[{"type":"Cases/families","qualification":"Case(s)","class":null,"value":30.0,"area":"Worldwide","status":"Validated","source":"[EXPERT]"},{"type":"Point prevalence","qualification":"Class only","class":"<1 / 1 000 000","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":null}