{"orpha":93337,"name":"Polydactyly of an index finger","type":"Morphological anomaly","group":"Disorder","status":"active","flags":[],"synonyms":["PPD3","Preaxial polydactyly type 3"],"definition":"Polydactyly of an index finger or PPD3 is a form of preaxial polydactyly of fingers, a limb malformation syndrome, where the thumb is replaced by one or two triphalangeal digits with dermatoglyphic pattern specific of the index finger. Two forms of PPD3 have been characterized: unilateral and bilateral. There have been no further descriptions in the literature since 1962.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-93337/","orphanet_url":"https://www.orpha.net/en/disease/detail/93337","names":{"fr":{"name":"Duplication de l'index","synonyms":["PPD3","Polydactylie de l'index","Polydactylie préaxiale type 3"],"definition":"La duplication de l'index ou PPD3 est une forme de polydactylie préaxiale des doigts, un syndrome malformatif des membres dans lequel le pouce est remplacé par un ou deux doigts triphalangés avec un schéma dermatoglyphique spécifique de l'index. Il existe deux formes de PPD3 : unilatérale et bilatérale. Il n'y a pas eu de description ultérieure dans la littérature depuis 1962."},"de":{"name":"Polydaktylie des Zeigefingers","synonyms":["PPD3","Polydaktylie, postaxiale, Typ 3"]},"es":{"name":"Polidactilia del dedo índice","synonyms":["PPD3","Polidactilia preaxial tipo 3"],"definition":"La polidactilia de un dedo índice o PPD3 es una forma de polidactilia preaxial de los dedos de la mano, un síndrome de malformación de las extremidades, en el que el pulgar es reemplazado por uno o dos dígitos trifalángicos con un patrón dermatoglífico específico del dedo índice. Se han caracterizado dos formas de PPD3: unilateral y bilateral. No ha habido más descripciones en la literatura desde 1962."},"it":{"name":"Polidattilia del dito indice","synonyms":["PPD3","Polidattilia preassiale, tipo 3"]},"nl":{"name":"Polydactylie van wijsvinger","synonyms":["PPD3","Preaxiale polydactylie type 3"],"definition":"Polydactylie van een wijsvinger of PPD3 is een vorm van pre-axiale polydactylie van de vingers (zie deze term), een ledemaatmalformatiesyndroom, waarbij de duim vervangen is door een of twee trifalangeale vingers met een dermatoglyfenpatroon specifiek voor de wijsvinger. Er zijn twee vormen van PPD3 gekarakteriseerd: unilateraal en bilateraal (zie deze termen). Er zijn geen verdere beschrijvingen in de literatuur sinds 1962."},"pt":{"name":"Polidactilia de um dedo indicador","synonyms":["PPD3","Polidactilia pré-axial tipo 3"]},"pl":{"name":"Polidaktylia palca wskazującego","synonyms":["PPD3","Przedosiowa polidaktylia typu 3"]},"cs":{"name":"Polydaktylie ukazováku ruky","synonyms":["PPD3","Preaxiální polydaktylie, typ 3"]},"uk":{"name":"Полідактилія вказівного пальця","synonyms":["PPD3","Преаксіальна полідактилія 3 типу"],"definition":"Polydactyly of an index finger or PPD3 is a form of preaxial polydactyly of fingers (see this term), a limb malformation syndrome, where the thumb is replaced by one or two triphalangeal digits with dermatoglyphic pattern specific of the index finger. Two forms of PPD3 have been characterized: unilateral and bilateral (see these terms). There have been no further descriptions in the literature since 1962."},"zh":{"name":"多食指畸形","synonyms":["轴前多指症3型"],"definition":"食指多指畸形（PPD3）是轴前多指畸形的一种类型，是一种肢体畸形综合征，其中拇指被一个或两个具有食指特定皮纹图案的三指节手指代替。PPD3有两种形式：单侧和双侧（见这些词条）。自1962年之后，没有文献对该病进行进一步的描述。"},"tr":{"name":"İşaret parmak polidaktilisi","synonyms":["PPD3","Preaksiyel polidaktili tip 3"]}},"xrefs":[{"source":"OMIM","code":"174600","qualifier":"E","icd_relation":null,"validated":true},{"source":"ICD-10","code":"Q69.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"LB78.Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"982050714"},{"source":"MONDO","code":"0008271","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"C566784","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C1868113","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"2256","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[{"type":"Referred to","orpha":295152,"name":"OBSOLETE: Polydactyly of an index finger, unilateral","status":"inactive"},{"type":"Referred to","orpha":295154,"name":"OBSOLETE: Polydactyly of an index finger, bilateral","status":"inactive"}],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":498464,"name":"Non-syndromic preaxial polydactyly","classifications":[147,156,199]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Autosomal dominant"],"onset":["Infancy","Neonatal"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"<1 / 1 000 000","value":0.0,"area":"Europe","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}