{"orpha":92,"name":"Juvenile idiopathic arthritis","type":"Clinical group","group":"Group of disorders","status":"active","flags":[],"synonyms":["Juvenile chronic arthritis","Juvenile rheumatoid arthritis"],"definition":"A rare, heterogeneous group of rheumatologic diseases characterized by arthritis which has an onset before 16 years of age, persists for more than 6 weeks, and is of unknown origin.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-92/","orphanet_url":"https://www.orpha.net/en/disease/detail/92","names":{"fr":{"name":"Arthrite juvénile idiopathique","synonyms":["Arthrite juvénile chronique","Arthrite juvénile rhumatoïde"],"definition":"Groupe hétérogène rare de maladies rhumatologiques caractérisées par une arthrite d'origine non connue qui débute avant l'âge de 16 ans et qui persiste pendant plus de 6 semaines."},"de":{"name":"Arthritis, idiopathische juvenile","synonyms":["Arthritis, chronische juvenile","Arthritis, juvenile rheumatische"],"definition":"Eine seltene, heterogene Gruppe rheumatologischer Erkrankungen, die durch eine Arthritis gekennzeichnet sind, die vor dem 16. Lebensjahr beginnt, länger als 6 Wochen anhält und deren Ursprung unbekannt ist."},"es":{"name":"Artritis idiopática juvenil","synonyms":["Artritis crónica juvenil","Artritis reumatoide juvenil"],"definition":"Es un grupo heterogéneo y poco frecuente de enfermedades reumatológicas caracterizadas por artritis que debuta antes de los 16 años, persistiendo durante más de 6 semanas y de etiología desconocida."},"it":{"name":"Artrite idiopatica giovanile","synonyms":["Artrite cronica giovanile","Artrite reumatoide giovanile"],"definition":"Comprende un gruppo eterogeneo di malattie reumatiche rare, caratterizzate da artrite ad esordio prima dei sedici anni che persiste per oltre sei settimane. L'eziologia non è nota."},"nl":{"name":"Juveniele idiopathische artritis","synonyms":["Juveniele chronische artritis","Juveniele reumatoïde artritis"],"definition":"Een zeldzame, heterogene groep of reumatische ziekten gekarakteriseerd door artritis die voor de leeftijd van 16 jaar aanvangt, langer dan 6 weken aanhoudt, en een ongekende oorsprong heeft."},"pt":{"name":"Artrite juvenil idiopática","synonyms":["Artrite crónica juvenil","Artrite reumatóide juvenil","Doença de Still"]},"pl":{"name":"Młodzieńcze idiopatyczne zapalenie stawów","synonyms":["Młodzieńcze przewlekłe zapalenie stawów","Młodzieńcze reumatoidalne zapalenie stawów"]},"cs":{"name":"Juvenilní idiopatická artritida","synonyms":["Juvenilní chronická artritida","Juvenilní revmatoidní artritida"]},"uk":{"name":"Ювенільний ідіопатичний артрит","synonyms":["Ювенільний хронічний артрит","Ювенільний ревматоїдний артрит"],"definition":"A rare, heterogeneous group of rheumatologic diseases characterized by arthritis which has an onset before 16 years of age, persists for more than 6 weeks, and is of unknown origin."},"zh":{"name":"青少年特发性关节炎","synonyms":["幼年型类风湿性关节炎"]},"tr":{"name":"Jüvenil idiopatik artriti","synonyms":["jüvenil kronik artrit","jüvenil romatoid artrit"]}},"xrefs":[{"source":"ICD-11","code":"FA24","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1322678686"},{"source":"MONDO","code":"0011429","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"11429","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D001171","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C3495559","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10059176","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98023,"name":"Rare systemic or rheumatologic disease"},"parents":[{"orpha":486955,"name":"Rare pediatric rheumatologic disease","classifications":[231]},{"orpha":182231,"name":"Rare rheumatologic disease","classifications":[196]},{"orpha":264704,"name":"Secondary interstitial lung disease specific to childhood associated with a connective tissue disease","classifications":[184,233]}],"children":[{"orpha":85438,"name":"Enthesitis-related juvenile idiopathic arthritis","type":"Disease"},{"orpha":85410,"name":"Oligoarticular juvenile idiopathic arthritis","type":"Disease"},{"orpha":404580,"name":"Polyarticular juvenile idiopathic arthritis","type":"Clinical group"},{"orpha":85436,"name":"Psoriasis-related juvenile idiopathic arthritis","type":"Disease"},{"orpha":85414,"name":"Systemic-onset juvenile idiopathic arthritis","type":"Disease"},{"orpha":91140,"name":"Unspecified juvenile idiopathic arthritis","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["Childhood"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"1-5 / 10 000","value":13.0,"area":"Czech Republic","status":"Validated","source":"17181917[PMID]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":1.5,"area":"Europe","status":"Validated","source":"[EXPERT]_ORPHANET"},{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 100 000","value":4.7,"area":"France","status":"Validated","source":"Haute Autorité de Santé 2009[OTHER]_ORPHANET_16821272[PMID]"},{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 100 000","value":8.9,"area":"United States","status":"Not yet validated","source":"23588938[PMID]_ORPHANET"},{"type":"Point prevalence","qualification":"Value and class","class":"1-5 / 10 000","value":21.0,"area":"Czech Republic","status":"Not yet validated","source":"17181917[PMID]_ORPHANET"},{"type":"Point prevalence","qualification":"Value and class","class":"1-5 / 10 000","value":20.5,"area":"Worldwide","status":"Validated","source":"24210707[PMID]"},{"type":"Point prevalence","qualification":"Value and class","class":"6-9 / 10 000","value":74.6,"area":"Specific population","status":"Validated","source":"31150159[PMID]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":7.8,"area":"Worldwide","status":"Validated","source":"24210707[PMID]"}],"phenotypes":null}