{"orpha":901,"name":"Wells syndrome","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Eosinophilic cellulitis"],"definition":"Wells syndrome is characterised by the presence of recurrent cellulitis-like eruptions with eosinophilia.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-901/","orphanet_url":"https://www.orpha.net/en/disease/detail/901","names":{"fr":{"name":"Syndrome de Wells","synonyms":["Cellulite à éosinophiles"],"definition":"Le syndrome de Wells se caractérise par une cellulite évoluant vers des éruptions récurrentes avec éosinophilie."},"de":{"name":"Wells-Syndrom","synonyms":["Zellulitis, eosinophile"],"definition":"Das Wells-Syndrom ist definiert als rezidivierendes, zellulitis-ähnliches Exanthem mit Eosinophilie."},"es":{"name":"Síndrome de Wells","definition":"El síndrome de Wells se caracteriza por la presencia de erupciones recurrentes de aspecto celulítico con eosinofilia."},"it":{"name":"Sindrome di Wells","synonyms":["Cellulite da eosinofili"]},"nl":{"name":"Syndroom van Wells","synonyms":["Eosinofiele cellulitis"],"definition":"Een syndroom, gekenmerkt door de aanwezigheid van recidiverende op cellulitis gelijkende erupties met eosinofilie."},"pt":{"name":"Síndrome Wells","synonyms":["Celulite eosinofílica"]},"pl":{"name":"Zespół Wellsa","synonyms":["Eozynofilowe zapalenie tkanki łącznej"]},"cs":{"name":"Wellsův syndrom","synonyms":["Eosinofilní celulitida"]},"uk":{"name":"Синдром Веллса","synonyms":["Еозинофільний целюліт"],"definition":"Wells syndrome is characterised by the presence of recurrent cellulitis-like eruptions with eosinophilia."},"zh":{"name":"韦尔斯综合征","synonyms":["嗜酸性蜂窝织炎"]},"tr":{"name":"Wells sendromu","synonyms":["Eozinofilik selülit"]}},"xrefs":[{"source":"ICD-10","code":"L98.3","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"EB30","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1860796142"},{"source":"MONDO","code":"0019547","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"C536693","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0343101","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"329","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10053776","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":89826,"name":"Rare skin disease"},"parents":[{"orpha":90077,"name":"Other acquired skin disease","classifications":[187]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adult"],"prevalence":[{"type":"Cases/families","qualification":"Case(s)","class":null,"value":200.0,"area":"Worldwide","status":"Validated","source":"23730155[PMID]"},{"type":"Point prevalence","qualification":"Class only","class":"<1 / 1 000 000","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET_23730155[PMID]"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2016-07-15","source":"25846461[PMID]_27357601[PMID]","terms":[{"hpo":"HP:0100658","label":"Cellulitis","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0000989","label":"Pruritus","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0008066","label":"Abnormal blistering of the skin","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000969","label":"Edema","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001880","label":"Increased total eosinophil count","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0200037","label":"Skin vesicle","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002829","label":"Arthralgia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001945","label":"Fever","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002633","label":"Vasculitis","frequency":"Excluded (0%)","criteria":null}]}}