{"orpha":90058,"name":"Spinal cord injury","type":"Particular clinical situation in a disease or syndrome","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":null,"note":null,"url":"https://raremap.alftech.space/d/ORPHA-90058/","orphanet_url":"https://www.orpha.net/en/disease/detail/90058","names":{"fr":{"name":"Lésion de la moelle épinière"},"de":{"name":"Rückenmarkverletzung"},"es":{"name":"Daño de la médula espinal"},"it":{"name":"Lesione del midollo spinale"},"nl":{"name":"Ruggenmergletsel"},"pt":{"name":"Lesão traumática da medula espinhal"},"pl":{"name":"Uraz rdzenia kręgowego"},"cs":{"name":"Poranění míchy"},"uk":{"name":"Травма спинного мозку"},"zh":{"name":"脊髓损伤"},"tr":{"name":"Omurilik yaralanması"}},"xrefs":[{"source":"ICD-10","code":"T09.3","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"ND51.2","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"2131180445"},{"source":"MONDO","code":"0043797","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D013119","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0037929","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10041552","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":102000,"name":"Medullar disease","classifications":[181]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Value and class","class":"1-5 / 10 000","value":32.0,"area":"Europe","status":"Validated","source":"European Medicines Agency[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":3.57,"area":"Canada","status":"Validated","source":"22337075[PMID]"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2023-10-05","source":"28161028[PMID]_32859390[PMID]_37761417[PMID]_28161027[PMID]","terms":[{"hpo":"HP:0100561","label":"Spinal cord lesion","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0012332","label":"Abnormal autonomic nervous system physiology","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002315","label":"Headache","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0003474","label":"Somatic sensory dysfunction","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001257","label":"Spasticity","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002839","label":"Urinary bladder sphincter dysfunction","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0010549","label":"Weakness due to upper motor neuron dysfunction","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0012533","label":"Allodynia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012534","label":"Dysesthesia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0003072","label":"Hypercalcemia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0007185","label":"Loss of consciousness","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002590","label":"Paralytic ileus","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0003396","label":"Syringomyelia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000016","label":"Urinary retention","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002953","label":"Vertebral compression fracture","frequency":"Occasional (29-5%)","criteria":null}]}}