{"orpha":90037,"name":"Drug-induced autoimmune hemolytic anemia","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Drug-induced AIHA"],"definition":"Drug-induced autoimmune hemolytic anemia is a type of autoimmune hemolytic anemia (AIHA) that occurs as a reaction to therapeutic drugs, and can be due to various mechanisms.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-90037/","orphanet_url":"https://www.orpha.net/en/disease/detail/90037","names":{"fr":{"name":"Anémie hémolytique auto-immune induite par les médicaments","synonyms":["AIHA induite par les médicaments"],"definition":"L'anémie hémolytique auto-immune induite par les médicaments est une forme d'anémie hémolytique auto-immune (AHAI) survenant en réaction à une administration médicamenteuse, selon divers mécanismes."},"de":{"name":"Anämie, autoimmun-hämolytische, Medikamenten-induzierte","definition":"Die Medikamenten-induzierte Autoimmun-hämolytische Anämie ist eine seltene Form der Autoimmun-hämolytischen Anämie (AIHA; s. dort), die unter verschiedenen Mechanismen als Folge von medikamentöser Therapie auftritt."},"es":{"name":"Anemia hemolítica autoinmune inducida por fármacos","synonyms":["AHAI inducida por fármacos","AIHA inducida por fármacos","Anemia hemolítica autoinmune inducida por medicamentos"],"definition":"La anemia hemolítica autoinmune inducida por medicamentos es un tipo de anemia hemolítica autoinmune (AIHA; consulte este término), que ocurre como reacción a medicamentos, y que puede estar provocada por diferentes mecanismos."},"it":{"name":"Anemia emolitica autoimmune farmaco-indotta","synonyms":["AIHA farmaco-indotta"]},"nl":{"name":"Medicatiegeïnduceerde auto-immune hemolytische anemie","synonyms":["Medicatiegeïnduceerde AIHA"],"definition":"Geneesmiddelgeïnduceerde auto-immune hemolytische anemie is een type van auto-immune hemolytische anemie (AIHA) dat optreedt als reactie op therapeutische medicatie, en kan te wijten zijn aan verschillende mechanismen."},"pt":{"name":"Anemia hemolítica autoimune induzida por fármacos","definition":"A anemia hemolítica autoimune induzida por fármacos é um tipo de anemia hemolítica autoimune (AIHA, ver este termo), que ocorre como uma reação a fármacos, e pode ser causada por vários mecanismos."},"pl":{"name":"Polekowa niedokrwistość autoimmunohemolityczna","synonyms":["AIHA polekowa"]},"cs":{"name":"Autoimunitní hemolytická anémie vyvolaná léky","synonyms":["AIHA vyvolaná léky"]},"uk":{"name":"Медикаментозна аутоімунна гемолітична анемія","synonyms":["Медикаментозна інтоксикація AIHA"],"definition":"Drug-induced autoimmune hemolytic anemia is a type of autoimmune hemolytic anemia (AIHA; see this term) that occurs as a reaction to therapeutic drugs, and can be due to various mechanisms."},"zh":{"name":"药物性自身免疫性溶血性贫血","synonyms":["药物诱导性AIHA"]},"tr":{"name":"İlaca bağlı otoimmün hemolitik anemi","synonyms":["İlaçla indüklenen AIHA"]}},"xrefs":[{"source":"ICD-10","code":"D59.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"3A20.Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1362381196"},{"source":"MONDO","code":"0019535","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0391817","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10055213","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97992,"name":"Rare hematologic disease"},"parents":[{"orpha":98375,"name":"Autoimmune hemolytic anemia","classifications":[194]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Multigenic/multifactorial"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"<1 / 1 000 000","value":0.0,"area":"Europe","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2016-06-01","source":null,"terms":[{"hpo":"HP:0001890","label":"Autoimmune hemolytic anemia","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0002875","label":"Exertional dyspnea","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0012378","label":"Fatigue","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0002315","label":"Headache","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001324","label":"Muscle weakness","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0000980","label":"Pallor","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0012086","label":"Abnormal urinary color","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001635","label":"Congestive heart failure","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0003573","label":"Increased total bilirubin","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001744","label":"Splenomegaly","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001649","label":"Tachycardia","frequency":"Occasional (29-5%)","criteria":null}]}}