{"orpha":90025,"name":"Non-syndromic syndactyly","type":"Category","group":"Group of disorders","status":"active","flags":[],"synonyms":[],"definition":"A group of rare, congenital, non-syndromic distal limb malformation disorders characterized by webbing or fusion of the fingers or toes, involving soft parts only or including bone structure. The morphological anomaly can be unilateral or bilateral, symmetrical or asymmetrical, depending on the specific type.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-90025/","orphanet_url":"https://www.orpha.net/en/disease/detail/90025","names":{"fr":{"name":"Syndactylie non syndromique","definition":"Groupe de maladies rares, congénitales, non syndromiques, consistant en malformation des membres distaux, caractérisées par des sangles ou une fusion des doigts ou des orteils, affectant uniquement les tissus mous, mais pouvant affecter aussi la structure osseuse. Sur le plan morphologique, la malformation peut être unilatérale ou bilatérale, symétrique ou asymétrique, selon le type spécifique."},"de":{"name":"Syndaktylie, nicht-syndromale","definition":"Eine Gruppe angeborener nicht-syndromaler Fehlbildungen der distalen Gliedmaßen, die durch eine Fusion von Fingern oder Zehen gekennzeichnet sind und nur die Weichteile oder auch die Knochenstruktur betreffen. Die morphologische Anomalie kann ein- oder beidseitig, symmetrisch oder asymmetrisch sein."},"es":{"name":"Sindactilia no sindrómica","definition":"Es un grupo de trastornos congénitos no sindrómicos poco frecuentes con malformación de las extremidades distales. Se caracteriza por membranas interdigitales o fusión de los dedos de las manos o los pies, que afectan únicamente a partes blandas o a estructuras óseas. Las anomalías morfológicas pueden ser unilaterales o bilaterales, simétricas o asimétricas, según el tipo específico."},"it":{"name":"Sindattilia non sindromica","definition":"Si tratta di un gruppo di malattie rare, congenite, non sindromiche da malformazione della porzione distale degli arti, caratterizzate da plicatura o fusione delle dita delle mani o dei piedi, che possono interessare solo i tessuti molli o anche la struttura ossea. L'anomalia morfologica può essere mono- o bilaterale, simmetrica o asimmetrica, a seconda della specifica tipologia."},"nl":{"name":"Niet-syndromale syndactylie","definition":"Een groep van zeldzame, congenitale, niet-syndromale aandoeningen met malformatie van distale ledematen, gekarakteriseerd door syndactylie of fusie van vingers of tenen, met enkel betrokkenheid van weke delen of ook van botstructuur. De morfologische anomalie is unilateraal of bilateraal, en symmetrisch of asymmetrisch, afhankelijk van het specifieke type."},"pt":{"name":"Sindactilia não-sindromática"},"pl":{"name":"Syndaktylia"},"cs":{"name":"Syndaktylie"},"uk":{"name":"Несиндромальна синдактилія","definition":"A group of rare, congenital, non-syndromic distal limb malformation disorders characterized by webbing or fusion of the fingers or toes, involving soft parts only or including bone structure. The morphological anomaly can be unilateral or bilateral, symmetrical or asymmetrical, depending on the specific type."},"zh":{"name":"非综合征型并指畸形"},"tr":{"name":"Sendromik olmayan sindaktili"}},"xrefs":[{"source":"ICD-10","code":"Q70","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"LB79","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1736296640"},{"source":"MONDO","code":"0019530","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"19530","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D013576","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5681365","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10042778","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":93458,"name":"Non-syndromic polydactyly, syndactyly and/or hyperphalangy","classifications":[147,156,199]}],"children":[{"orpha":157801,"name":"Mesoaxial synostotic syndactyly with phalangeal reduction","type":"Morphological anomaly"},{"orpha":93402,"name":"Syndactyly type 1","type":"Morphological anomaly"},{"orpha":93403,"name":"Syndactyly type 2","type":"Morphological anomaly"},{"orpha":93404,"name":"Syndactyly type 3","type":"Morphological anomaly"},{"orpha":93405,"name":"Syndactyly type 4","type":"Morphological anomaly"},{"orpha":93406,"name":"Syndactyly type 5","type":"Morphological anomaly"},{"orpha":295012,"name":"Syndactyly type 6","type":"Morphological anomaly"},{"orpha":2498,"name":"Syndactyly type 8","type":"Morphological anomaly"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}