{"orpha":90021,"name":"Radiation myelitis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"Radiation myelitis is a rare neurological disease characterized by the development of paresthesias, as well as, in severe cases, progressive paresis and paralysis following irradiation of tumors in which the spinal cord is included within the radiation field. Symptoms may develop months or years after radiation therapy was administered.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-90021/","orphanet_url":"https://www.orpha.net/en/disease/detail/90021","names":{"fr":{"name":"Myélite radique","synonyms":["Myélite post-radique"],"definition":"La myélite radique est une maladie neurologique rare caractérisée par le développement d'une paresthésie, et dans les cas sévères, d'une parésie et d'une paralysie progressives, suite à l'irradiation de tumeurs et l'atteinte de la moelle épinière dans le champ de radiation. Les signes peuvent se développer des mois ou des années après l'administration de la radiothérapie."},"de":{"name":"Myelitis, radiogene","synonyms":["Strahlenmyelitis","Strahlenmyelopathie"],"definition":"Die Strahlenmyelitis ist eine seltene neurologische Erkrankung, die durch die Entwicklung von Parästhesien sowie in schweren Fällen durch fortschreitende Paresen und Lähmungen nach Bestrahlung von Tumoren gekennzeichnet ist, bei denen das Rückenmark in das Strahlenfeld einbezogen ist. Die Symptome können Monate oder Jahre nach der Strahlentherapie auftreten."},"es":{"name":"Mielitis por radiación","definition":"La mielitis por radiación es una complicación neurológica poco frecuente de la radioterapia, caracterizada por el desarrollo de parestesias, y en los casos graves, parálisis progresiva que ocurre tras la irradiación de tumores en los que la médula espinal está incluida dentro del campo de radiación. Los síntomas pueden aparecer meses o años después de que se administrase la radioterapia."},"it":{"name":"Mielite da radiazioni","definition":"La mielite da radiazioni è una malattia neurologica rara caratterizzata da parestesie e, nei casi più gravi, paresi progressiva e paralisi, secondarie all'irradiazione di tumori per il cui trattamento il midollo spinale rientrava nel campo di radiazione. I sintomi possono insorgere a distanza di mesi o anni dopo la conclusione della radioterapia."},"nl":{"name":"Radiatiemyelitis","definition":"Radiatiemyelitis is een zeldzame neurologische ziekte die gekarakteriseerd wordt door de ontwikkeling van paresthesieën, alsook, in ernstige gevallen, van progressieve parese en paralyse na bestraling van tumoren waarbij het ruggenmerg deel uitmaakt van het bestralingsgebied. Symptomen kunnen maanden of jaren nadat radiotherapie werd toegediend, ontwikkelen."},"pt":{"name":"Mielite por radiação"},"pl":{"name":"Popromienne zapalenie rdzenia kręgowego"},"cs":{"name":"Radiační myelitida"},"uk":{"name":"Променевий мієліт","definition":"Radiation myelitis is a rare neurological disease characterized by the development of paresthesias, as well as, in severe cases, progressive paresis and paralysis following irradiation of tumors in which the spinal cord is included within the radiation field. Symptoms may develop months or years after radiation therapy was administered."},"zh":{"name":"放射性脊髓炎"},"tr":{"name":"Radyasyon miyeliti"}},"xrefs":[{"source":"ICD-10","code":"G97.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"NF00","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0019529","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4706614","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":102000,"name":"Medullar disease","classifications":[181]},{"orpha":521132,"name":"Radiation-induced disorder","classifications":[204]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}