{"orpha":879,"name":"Tungiasis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"Tungiasis is a parasitic skin disease caused by the female sand flea <i>Tunga penetrans</i>. The disease is characterized by acute (multiple white, gray, or yellowish papular or nodular lesions with brown-black-colored opening at the center and peripheral erythema) and chronic inflammation in the feet with itchy/ painful lesions. Bacterial superinfection is common and result in debilitating clinical pathology (deep ulcers, gangrene, lymphangitis and septicemia), leading to impaired physical fitness and mobility. Tungiasis also involves hyperkeratosis, fissuration, nail hypertrophy, and loss of nails.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-879/","orphanet_url":"https://www.orpha.net/en/disease/detail/879","names":{"fr":{"name":"Tungose","definition":"La tungose est une maladie cutanée parasitaire causée par la puce-chique femelle <i>Tunga penetrans</i>. La maladie est caractérisée par une inflammation aiguë (multiples lésions papulaires ou nodulaires blanches, grises ou jaunâtres avec une ouverture colorée marron-noire au centre et un érythème périphérique) et chronique au niveau des pieds, avec des lésions prurigineuses/douloureuses. La surinfection bactérienne est fréquente et résulte en une pathologie clinique invalidante (ulcères profondes, gangrène, lymphangite et septicémie), conduisant à l'altération de la condition physique et de la mobilité. La tungose implique également une hyperkératose, une fissuration, une hypertrophie des ongles et la perte des ongles."},"de":{"name":"Tungiasis"},"es":{"name":"Tungosis","definition":"Es una enfermedad parasitaria de la piel causada por las hembras de la pulga de arena <i>Tunga penetrans</i>. La enfermedad está caracterizada por inflamación aguda (múltiples lesiones papulares o nodulares blancas, grisaceas o amarillentas con una abertura de color marrón negruzco en el centro y eritema periférico) y crónica de los pies, con lesiones pruriginosas/dolorosas. La sobreinfección bacteriana es común y da como resultado una patología clínica debilitante (úlceras profundas, gangrena, linfangitis y septicemia), lo que conduce a un deterioro de la condición física y de la movilidad. La tungiasis también implica hiperqueratosis, fisuras, hipertrofia ungueal y pérdida de uñas."},"it":{"name":"Tungosi"},"nl":{"name":"Tungiasis","definition":"Tungiasis is een parasitaire huidziekte die veroorzaakt wordt door de vrouwelijke zandvlo <i>Tunga penetrans</i>. De ziekte wordt gekenmerkt door acute (meervoudige witte, grijze of geelachtige papulaire of nodulaire laesies met bruinzwart gekleurde opening in het midden en perifeer erytheem) en chronische inflammatie in de voeten die leidt tot de ontwikkeling van jeukende/pijnlijke laesies. Een bacteriële superinfectie is algemeen en resulteert in een verzwakkende klinische pathologie (diepe zweren, gangreen, lymfangitis en septicemie), wat leidt tot een verstoorde fysieke gezondheid en mobiliteit. Tungiasis veroorzaakt ook hyperkeratose, fissuratie, hypertrofie van nagels, en verlies van nagels."},"pt":{"name":"Tungiose"},"pl":{"name":"Tungiaza"},"cs":{"name":"Tungiáza"},"uk":{"name":"Тунгіаз","definition":"Tungiasis is a parasitic skin disease caused by the female sand flea <i>Tunga penetrans</i>. The disease is characterized by acute (multiple white, gray, or yellowish papular or nodular lesions with brown-black-colored opening at the center and peripheral erythema) and chronic inflammation in the feet with itchy/ painful lesions. Bacterial superinfection is common and result in debilitating clinical pathology (deep ulcers, gangrene, lymphangitis and septicemia), leading to impaired physical fitness and mobility. Tungiasis also involves hyperkeratosis, fissuration, nail hypertrophy, and loss of nails."},"zh":{"name":"潜蚤病"},"tr":{"name":"Tungiyaz"}},"xrefs":[{"source":"ICD-10","code":"B88.1","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"1G05","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"2076748409"},{"source":"MONDO","code":"0019498","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D058285","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0277356","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"393","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":163588,"name":"Rare parasitic disease","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"22941398[PMID]"}],"phenotypes":null}