{"orpha":86846,"name":"Therapy related acute myeloid leukemia and myelodysplastic syndrome","type":"Category","group":"Group of disorders","status":"active","flags":[],"synonyms":["Secondary AML","Secondary acute myeloid leukemia","Therapy-related AML and myelodysplastic syndrome"],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-86846/","orphanet_url":"https://www.orpha.net/en/disease/detail/86846","names":{"fr":{"name":"Leucémie aiguë myéloïde et syndromes myélodysplasiques thérapie-dépendants","synonyms":["Leucémie aiguë myéloïde secondaire"]},"de":{"name":"Therapiebedingte akute myeloische Leukämie und myelodysplastische Syndrome","synonyms":["Sekundäre AML","Sekundäre akute myeloische Leukämie","Therapiebedingte AML und MDS"]},"es":{"name":"Síndrome mielodisplásico y leucemia mieloide aguda asociados al tratamiento","synonyms":["LMA secundaria","Leucemia mieloide aguda secundaria","Síndrome mielodisplásico y LMA asociados al tratamiento"]},"it":{"name":"Leucemia mieloide acuta e sindrome mielodisplastica, terapia-dipendenti","synonyms":["AML e sindrome mielodisplastica, terapia-dipendenti","AML secondaria","Leucemia mieloide acuta secondaria"]},"nl":{"name":"Therapiegerelateerde acute myeloïde leukemie en myelodysplastisch syndroom","synonyms":["Secundaire AML","Secundaire acute myeloïde leukemie","Therapiegerelateerde AML en myelodysplastisch syndroom"]},"pt":{"name":"Leucemia mielóide aguda e síndromes mielodisplásicos, relacionados com a terapia"},"pl":{"name":"Polekowa ostra białaczka szpikowa i zespół mielodysplastyczny","synonyms":["Polekowa AML i zespół mielodysplastyczny","Wtórna AML","Wtórna ostra białaczka szpikowa"]},"cs":{"name":"Akutní myeloidní leukémie a myelodysplastický syndrom způsobené terapií","synonyms":["Sekundární AML","Sekundární akutní myeloidní leukémie","AML a myelodysplastický syndrom způsobené terapií"]},"uk":{"name":"Терапія-повязана гостра мієлоїдна лейкемія та мієлодиспластичний синдром","synonyms":["Вторинна гостра мієлоїдна лейкемія","Вторинний ГМЛ","ГМЛ, повязаний з терапією, та мієлодиспластичний синдром"]},"zh":{"name":"治疗相关性急性髓系白血病和骨髓增生异常综合征","synonyms":["治疗相关性AML伴骨髓增生异常综合征"]},"tr":{"name":"Tedaviye bağlı akut miyeloid lösemi ve miyelodisplastik sendrom","synonyms":["Sekonder AML","Sekonder akut miyeloid lösemi","Tedaviye bağlı AML ve miyelodisplastik sendrom"]}},"xrefs":[{"source":"OMIM","code":"601626","qualifier":"NTBT","icd_relation":null,"validated":true},{"source":"ICD-11","code":"2A60.20","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1581599493"},{"source":"MONDO","code":"0019457","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"19457","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C1292776","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":519,"name":"Acute myeloid leukemia","classifications":[194,202,233]}],"children":[{"orpha":102379,"name":"Acute myeloid leukemia and myelodysplastic syndromes related to alkylating agent","type":"Disease"},{"orpha":164726,"name":"Acute myeloid leukemia and myelodysplastic syndromes related to radiation","type":"Disease"},{"orpha":102381,"name":"Acute myeloid leukemia and myelodysplastic syndromes related to topoisomerase type 2 inhibitor","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["All ages"],"prevalence":[{"type":"Annual incidence","qualification":"Class only","class":"<1 / 1 000 000","value":0.0,"area":"Europe","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"}],"phenotypes":null}