{"orpha":84065,"name":"Idiopathic malabsorption due to bile acid synthesis defects","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Idiopathic bile acid malabsorption"],"definition":"A disorder that is due to increased acid bile synthesis is an intestinal disease of unknown etiology characterized by an overproduction of bile acids which leads to chronic watery diarrhea.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-84065/","orphanet_url":"https://www.orpha.net/en/disease/detail/84065","names":{"fr":{"name":"Malabsorption idiopathique par défaut de synthèse des acides biliaires","definition":"La malabsorption idiopathique par défaut de synthèse des acides biliaires est une maladie intestinale d'étiologie inconnue caractérisée par une surproduction d'acides biliaires entraînant une diarrhée liquide chronique."},"de":{"name":"Malabsorption durch Gallensäuresynthesedefekt, idiopathische Form","definition":"Die Idiopathische Malabsorption durch vermehrte Gallensäuren-Synthese ist eine Darmerkrankrankung mit unbekannter Ursache. Überproduktion von Gallensäuren führt zu chronischer wässriger Diarrhoe."},"es":{"name":"Malabsoción idiopática por defectos de la síntesis de ácidos biliares","definition":"Es un trastorno debido a un aumento en la síntesis de ácidos biliares es una enfermedad intestinal de etiología desconocida que se caracteriza por una sobreproducción de ácidos biliares que dan lugar a una diarrea acuosa crónica."},"it":{"name":"Malassorbimento idiopatico da difetto della sintesi degli acidi biliari","synonyms":["Malassorbimento idiopatico degli acidi biliari"],"definition":"Il malassorbimento idiopatico da aumento della sintesi degli acidi biliari è una malattia intestinale ad eziologia sconosciuta, caratterizzata dall'iperproduzione di acidi biliari, con diarrea acquosa cronica secondaria."},"nl":{"name":"Idiopathische malabsorptie door defecten van galzuursynthese","synonyms":["Idiopathische galzuurmalabsorptie"],"definition":"Een aandoening veroorzaakt door verhoogde synthese van galzuur is een darmziekte met ongekende etiologie en gekarakteriseerd door een overproductie van galzuren, wat leidt tot chronische waterige diarree."},"pt":{"name":"Má absorção idiopática por defeitos da síntese de ácidos biliares","synonyms":["Má absorção idiopática de ácidos biliares"]},"pl":{"name":"Idiopatyczny zespół złego wchłaniania z powodu defektu syntezy kwasów żółciowych","synonyms":["Idiopatyczne złe wchłanianie kwasów żółciowych"]},"cs":{"name":"Idiopatická malabsorpce způsobená poruchou syntézy žlučových kyselin","synonyms":["Idiopatická malabsorpce žlučových kyselin"]},"uk":{"name":"Ідіопатична мальабсорбція через дефекти синтезу жовчних кислот","synonyms":["Ідіопатична мальабсорбція жовчних кислот"],"definition":"A dirsorder that is due to increased acid bile synthesis is an intestinal disease of unknown etiology characterized by an overproduction of bile acids which leads to chronic watery diarrhea."},"zh":{"name":"胆酸合成缺陷所致特发性吸收不良","synonyms":["特发性胆汁酸吸收障碍"]},"tr":{"name":"Safra asidi sentez defektlerine bağlı idiyopatik malabsorpsiyon","synonyms":["İdiyopatik safra asidi malabsorpsiyonu"]}},"xrefs":[{"source":"ICD-10","code":"K90.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"DA96.02","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"140648189"},{"source":"MONDO","code":"0019393","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4274509","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97935,"name":"Rare gastroenterologic disease"},"parents":[{"orpha":79168,"name":"Disorder of bile acid synthesis","classifications":[150]},{"orpha":104005,"name":"Intestinal disease due to fat malabsorption","classifications":[152]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}