{"orpha":83593,"name":"Western equine encephalitis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Western equine encephalomyelitis"],"definition":"An acute arboviral infection caused by an <i>alphavirus</i> of the <i>Togaviridae</i> family transmitted by an infected mosquito, that more frequently affects children and that is characterized by the presence of mild flu-like symptoms (fever, chills, headache, nausea, vomiting, and anorexia) but that can progress to weakness, altered mental status, photophobia, mental confusion, seizures, somnolence, coma and/or even death. The disease can leave neurological sequelae, mainly in infants and children, such as seizures, spasticity or behavioral disorders.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-83593/","orphanet_url":"https://www.orpha.net/en/disease/detail/83593","names":{"fr":{"name":"Encéphalite équine de l'ouest","synonyms":["Encéphalomyélite équine de l'ouest"],"definition":"Infection aiguë causée par un arbovirus du genre alphavirus, de la famille des <i>Togaviridae</i> transmis par un moustique infecté. Elle touche plus fréquemment les enfants et se caractérise par des symptômes bénins de type fébrile (fièvre, frissons, maux de tête, nausées, vomissements et anorexie) mais qui peuvent évoluer vers une faiblesse, une altération de l'état mental, une photophobie, une confusion mentale, des convulsions, une somnolence, un coma, voire un décès. La maladie peut laisser des séquelles neurologiques à type de crises d'épilepsie, de spasticité ou de troubles du comportement, principalement chez les nourrissons et les enfants."},"de":{"name":"Westliche Pferdeenzephalitis","synonyms":["Western-Equine-Encephalitis"]},"es":{"name":"Encefalitis equina occidental","synonyms":["Encefalomielitis equina occidental"],"definition":"Es una infección arboviral aguda causada por un <i>Alfavirus</i> de la familia <i>Togaviridae</i> transmitida por un mosquito infectado. Afecta con mayor frecuencia a los niños y está caracterizada por la presencia de síntomas leves similares a los de la gripe (fiebre, escalofríos, cefalea, náuseas, vómitos y anorexia) aunque puede progresar a debilidad, alteración del estado mental, fotofobia, confusión mental, convulsiones, somnolencia, coma y/o incluso la muerte. La enfermedad puede dejar secuelas neurológicas, tales como crisis epilépticas, espasticidad o trastornos de conducta, principalmente en lactantes y en niños."},"it":{"name":"Encefalite equina dell'Ovest","synonyms":["Encefalomielite equina dell'Ovest"]},"nl":{"name":"Westerse paardenencefalitis","synonyms":["Westerse equine encefalitis","Westerse paardenencefalomyelitis"],"definition":"Een acute arbovirale infectie veroorzaakt door een <i>alphavirus</i> van de <i>Togaviridae</i>-familie en overgedragen door een geïnfecteerde mug. De infectie treft vaker kinderen en wordt gekarakteriseerd door de aanwezigheid van mild griepachtige symptomen (koorts, koude rillingen, hoofdpijn, misselijkheid, braken, en anorexie), maar kan evolueren tot zwakheid, gewijzigde mentale toestand, fotofobie, mentale verwardheid, insulten, slaperigheid, coma en/of zelfs overlijden. De ziekte kan neurologische restverschijnselen nalaten, vooral bij zuigelingen en kinderen, zoals insulten, spasticiteit of gedragsstoornissen."},"pt":{"name":"Encefalite equina ocidental","synonyms":["Encefalomielite equina ocidental"]},"pl":{"name":"Zachodnie końskie zapalenie mózgu","synonyms":["Zachodnie końskie zapalenie mózgu i opon mózgowych"]},"cs":{"name":"Západní koňská encefalitida","synonyms":["Západní koňská encefalomyelitida"]},"uk":{"name":"Західний кінський енцефаліт","synonyms":["Західний енцефаломієліт коней"],"definition":"An acute arboviral infection caused by an <i>alphavirus</i> of the <i>Togaviridae</i> family transmitted by an infected mosquito, that more frequently affects children and that is characterized by the presence of mild flulike symptoms (fever, chills, headache, nausea, vomiting, and anorexia) but that can progress to weakness, altered mental status, photophobia, mental confusion, seizures, somnolence, coma and/or even death. The disease can leave neurological sequelae, mainly in infants and children, such as seizures, spasticity or behavioral disorders."},"zh":{"name":"西方马脑炎","synonyms":["西部马脑脊髓炎"]},"tr":{"name":"Batı at ensefaliti","synonyms":["Batı at ensefalomiyeliti"]}},"xrefs":[{"source":"ICD-10","code":"A83.1","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"1C83","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1543765035"},{"source":"MONDO","code":"0019380","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D020241","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0153064","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"7888","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10014614","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":166490,"name":"Infectious disease with epilepsy","classifications":[181]},{"orpha":98252,"name":"Infectious encephalitis","classifications":[181,203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.02,"area":"United States","status":"Validated","source":"Center for Diseases Control and Prevention[OTHER]"},{"type":"Point prevalence","qualification":"Class only","class":"1-9 / 1 000 000","value":0.0,"area":"Europe","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}