{"orpha":83483,"name":"La Crosse encephalitis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Californian encephalitis"],"definition":"An acute arboviral infection caused by the <i>La Crosse bunyavirus</i> transmitted by an infected mosquito, usually observed in infants, children or adolescents (6 months to 16 years), and characterized by the onset of flulike symptoms such as fever, chills, nausea, vomiting, headache, and abdominal pain, followed by the onset of encephalitis characterized by somnolence, obtundation, and even seizures, focal neurologic signs (asymmetrical reflexes or Babinski signs), paralysis or even coma. CE can leave sequelae such as residual epilepsy and neurocognitive deficits.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-83483/","orphanet_url":"https://www.orpha.net/en/disease/detail/83483","names":{"fr":{"name":"Encéphalite de La Crosse","synonyms":["Encéphalite de Californie"],"definition":"Infection aiguë à arbovirus causée par le virus de La Crosse, famille des <i>Bunyaviridae</i> transmis par un moustique infecté, généralement observée chez les nourrissons, les enfants ou les adolescents (âgés de 6&nbsp;mois à 16&nbsp;ans), et caractérisée par l'apparition de symptômes de type fébrile tels qu'une fièvre, des frissons, des nausées, des vomissements, des maux de tête et des douleurs abdominales, suivis par l'apparition d'une encéphalite caractérisée par une somnolence, une obtusion, voire des crises convulsives, des signes neurologiques focaux (réflexes asymétriques ou signes de Babinski), une paralysie, voire un coma. L'encéphalite peut laisser des séquelles telles qu'une épilepsie résiduelle et des troubles neurocognitifs."},"de":{"name":"Kalifornische Enzephalitis"},"es":{"name":"Encefalitis de La Crosse","synonyms":["Encefalitis californiana"],"definition":"Es una infección arboviral aguda causada por el virus de La Crosse, perteneciente a la familia <i>Bunyaviridae</i>, transmitida por un mosquito infectado y, generalmente descrita en lactantes, niños o adolescentes (de 6 meses a 16 años de edad). Está caracterizada por un inicio de síntomas similares a la gripe, tales como fiebre, escalofríos, náuseas, vómitos, cefalea y dolor abdominal, seguidos por la aparición de encefalitis que se manifiesta como somnolencia, obnubilación y posibles crisis epilépticas, signos neurológicos focales (reflejos asimétricos o signo de Babinski), parálisis e incluso coma. La infección puede dejar secuelas tales como epilepsias residuales y déficits neurocognitivos."},"it":{"name":"Encefalite di La Crosse","synonyms":["Encefalite californiana"]},"nl":{"name":"La Crosse-encefalitis","synonyms":["Californië-encefalitis"],"definition":"Een acute arbovirale infectie veroorzaakt door <i>bunyavirus La Crosse</i> en overgedragen door een geïnfecteerde mug. De infectie wordt meestal waargenomen bij zuigelingen, kinderen of adolescenten (6 maanden tot 16 jaar), en wordt gekarakteriseerd door aanvang van griepachtige symptomen zoals koorts, koude rillingen, misselijkheid, braken, hoofdpijn, en abdominale pijn, gevolgd door aanvang van encefalitis gekenmerkt door slaperigheid, obtundatie, en zelfs insulten, focale neurologische tekenen (asymmetrische reflexen of Babinski-tekenen), verlamming of zelfs coma. CE kan restverschijnselen nalaten zoals residuele epilepsie en neurocognitieve gebreken."},"pt":{"name":"Encefalite da Califórnia"},"pl":{"name":"Zapalenie mózgu La Crosse","synonyms":["Kalifornijskie zapalenie mózgu"]},"cs":{"name":"La Crossova encefalitida","synonyms":["Kalifornská encefalitida"]},"uk":{"name":"Енцефаліт Ла-Кросса","synonyms":["Каліфорнійський енцефаліт"],"definition":"An acute arboviral infection caused by the <i>La Crosse bunyavirus</i> transmitted by an infected mosquito, usually observed in infants, children or adolescents (6 months to 16 years), and characterized by the onset of flulike symptoms such as fever, chills, nausea, vomiting, headache, and abdominal pain, followed by the onset of encephalitis characterized by somnolence, obtundation, and even seizures, focal neurologic signs (asymmetrical reflexes or Babinski signs), paralysis or even coma. CE can leave sequelae such as residual epilepsy and neurocognitive deficits."},"zh":{"name":"大地病毒脑炎","synonyms":["加利福尼亚脑炎"]},"tr":{"name":"La Crosse ensefaliti","synonyms":["Kaliforniya ensefaliti"]}},"xrefs":[{"source":"ICD-10","code":"A83.5","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"1C8D","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1501615629"},{"source":"MONDO","code":"0019378","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D004670","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0276379","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"10925","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10014584","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":166490,"name":"Infectious disease with epilepsy","classifications":[181]},{"orpha":98252,"name":"Infectious encephalitis","classifications":[181,203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":1.91,"area":"Canada","status":"Validated","source":"Canada Public Health Agency[OTHER]"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}