{"orpha":83476,"name":"West-Nile encephalitis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["West-Nile fever"],"definition":"An acute arboviral infection caused by a virus of the <i>Flaviviridae</i> family transmitted by an infected mosquito, that is asymptomatic in the majority of cases but that can present in rare occasions with mild flulike symptoms such as low-grade fever, arthralgia, myalgia, and/or rash, or with neurologic manifestations including meningitis, encephalitis with mental confusion or disorientation, tremors and acute flaccid paralysis/poliomyelitis.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-83476/","orphanet_url":"https://www.orpha.net/en/disease/detail/83476","names":{"fr":{"name":"Encéphalite West-Nile","synonyms":["Fièvre West-Nile"],"definition":"Infection aiguë à arbovirus causée par un virus de la famille des <i>Flaviviridae</i> transmis par un moustique infecté. Généralement asymptomatique, l'infection peut se manifester dans de rares cas par des symptômes bénins de type fébrile tels qu'une fièvre légère, des arthralgies, des myalgies et/ou des éruptions cutanées, ou par des manifestations neurologiques à type de méningite, d'encéphalite avec confusion mentale ou désorientation, de tremblements et de paralysie flasque aiguë/de poliomyélite."},"de":{"name":"West-Nil-Enzephalitis","synonyms":["West-Nil-Fieber"],"definition":"Die West-Nil-Enzephalitis (WNE) ist eine akute arbovirale Infektion, die durch ein Mücken übertragenes Virus der Familie Flaviviridae verursacht wird und zumeist asymptomatisch verläuft. In seltenen Fällen können leichte grippeähnliche Symptome wie Fieber, Arthralgie, Myalgie und/oder Ausschlag oder neurologische Manifestationen wie Meningitis, Enzephalitis mit geistiger Verwirrung oder Desorientierung, Zittern und akuter schlaffer Lähmung/Poliomyelitis auftreten."},"es":{"name":"Encefalitis del Nilo occidental","synonyms":["Fiebre del Nilo occidental"],"definition":"Es una infección arboviral aguda causada por un virus de la familia <i>Flaviviridae</i> transmitido por un mosquito infectado. En la mayoría de los casos es asintomática, aunque puede presentarse excepcionalmente con síntomas leves similares a la gripe, tales como febrícula, artralgia, mialgia y/o erupción cutánea, o con manifestaciones neurológicas que incluyen meningitis, encefalitis con confusión mental o desorientación, temblores y parálisis flácida aguda/poliomielitis."},"it":{"name":"Encefalite del Nilo occidentale","synonyms":["Febbre del Nilo occidentale"]},"nl":{"name":"West-Nijl-encefalitis","synonyms":["West-Nijl-koorts","Westnijlkoorts"],"definition":"Een acute arbovirale infectie veroorzaakt door een virus van de <i>Flaviviridae</i>-familie en overgedragen door een geïnfecteerde mug. In de meerderheid van de gevallen is de infectie asymptomatisch, maar in zeldzame gevallen kunnen milde griepachtige symptomen optreden, waaronder lichte koorts, artralgie, myalgie, en/of huiduitslag, of neurologische manifestaties waaronder meningitis, encefalitis met mentale verwardheid of desoriëntatie, tremor en acute slappe paralyse/poliomyelitis."},"pt":{"name":"Encefalia do Oeste do Nilo","synonyms":["Febre do Oeste do Nilo"]},"pl":{"name":"Zapalenie mózgu Zachodniego Nilu","synonyms":["Gorączka Zachodniego Nilu"]},"cs":{"name":"Západonilská encefalitida","synonyms":["Západonilská horečka"]},"uk":{"name":"Енцефаліт Західного Нілу","synonyms":["Лихоманка Західного Нілу"],"definition":"An acute arboviral infection caused by a virus of the <i>Flaviviridae</i> family transmitted by an infected mosquito, that is asymptomatic in the majority of cases but that can present in rare occasions with mild flulike symptoms such as low-grade fever, arthralgia, myalgia, and/or rash, or with neurologic manifestations including meningitis, encephalitis with mental confusion or disorientation, tremors and acute flaccid paralysis/poliomyelitis."},"zh":{"name":"西尼罗脑炎","synonyms":["西尼罗热"]},"tr":{"name":"Batı Nil ensefaliti","synonyms":["Batı-Nil ateşi"]}},"xrefs":[{"source":"OMIM","code":"610379","qualifier":"BTNT","icd_relation":null,"validated":true},{"source":"ICD-10","code":"A92.3","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"1C80","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1659165624"},{"source":"MONDO","code":"0019376","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D014901","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0751583","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"9959","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":166490,"name":"Infectious disease with epilepsy","classifications":[181]},{"orpha":98252,"name":"Infectious encephalitis","classifications":[181,203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.92,"area":"United States","status":"Validated","source":"23013055[PMID]_Center for Diseases Control and Prevention 2012[OTHER]"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.036,"area":"Europe","status":"Validated","source":"European Centre for Disease prevention and Control 2011-2015[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.12,"area":"Romania","status":"Validated","source":"European Centre for Disease prevention and Control 2011-2015[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.02,"area":"Austria","status":"Validated","source":"European Centre for Disease prevention and Control 2011-2015[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.17,"area":"Croatia","status":"Validated","source":"European Centre for Disease prevention and Control 2012-2015[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.66,"area":"Greece","status":"Validated","source":"European Centre for Disease prevention and Control 2011-2015[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.16,"area":"Hungary","status":"Validated","source":"European Centre for Disease prevention and Control 2011-2015[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.07,"area":"Italy","status":"Validated","source":"European Centre for Disease prevention and Control 2011-2013[OTHER]"}],"phenotypes":null}