{"orpha":83468,"name":"Solitary bone cyst","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Juvenile bone cyst"],"definition":"A benign non-epithelial bone cavity that is asymptomatic and that is found most commonly in the second decade of life by chance. The long bones are most often affected, but cases involving the jaw bone have been reported.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-83468/","orphanet_url":"https://www.orpha.net/en/disease/detail/83468","names":{"fr":{"name":"Kyste osseux solitaire","synonyms":["Kyste osseux juvénile"],"definition":"Cavité osseuse bénigne non épithéliale, asymptomatique, généralement identifiée de manière fortuite, le plus souvent au cours de la deuxième décennie de la vie. Les os longs sont les plus souvent touchés, mais des cas d'atteinte de l'os de la mâchoire ont été rapportés."},"de":{"name":"Knochenzyste, solitäre","synonyms":["Knochenzyste, juvenile"],"definition":"Die solitäre Knochenzyste ist eine benigne, nicht-epithelialisierte Knochenhöhle, die keine Symptome verursacht und in der Regel im zweiten Lebensjahrzehnt zufällig entdeckt wird. Am häufigsten sind die langen Knochen betroffen, aber auch Fälle mit Befall des Kiefers wurden beschrieben."},"es":{"name":"Quiste óseo solitario","synonyms":["Quiste óseo juvenil"],"definition":"Es una cavidad ósea no epitelial benigna asintomática que se detecta generalmente en la segunda década de vida de forma casual. Los huesos largos son los afectados con mayor frecuencia, pero se han descrito casos que afectan al hueso de la mandíbula."},"it":{"name":"Cisti ossea solitaria","synonyms":["Cisti ossea giovanile"],"definition":"La cisti ossea solitaria è una cavità ossea benigna, non epiteliale, asintomatica, di solito identificata incidentalmente, più spesso nella seconda decade di vita. Sono interessate più comunemente le ossa lunghe, ma sono stati segnalati casi con coinvolgimento della mascella."},"nl":{"name":"Solitaire botcyste","synonyms":["Juveniele botcyste"],"definition":"Een goedaardige, niet-epitheliale botholte die asymptomatisch is en die meestal per toeval wordt aangetroffen in het tweede levensdecennium. Pijpbeenderen worden het vaakst aangetast, maar er werden gevallen met betrokkenheid van kaakbeen gerapporteerd."},"pt":{"name":"Quisto ósseo solitário","synonyms":["Quisto ósseo juvenil"]},"pl":{"name":"Pojedyńcza torbiel kości","synonyms":["Pojedyńcza torbiel kostna"]},"cs":{"name":"Solitární kostní cysta","synonyms":["Jednokomorová kostní cysta"]},"uk":{"name":"Солітарна кісткова кіста","synonyms":["Однокамерна кістома кістки"],"definition":"A benign non-epithelial bone cavity that is asymptomatic and that is found most commonly in the second decade of life by chance. The long bones are most often affected, but cases involving the jaw bone have been reported."},"zh":{"name":"单一性骨囊肿","synonyms":["单房性骨囊肿"]},"tr":{"name":"Soliter kemik kisti","synonyms":["Tek kamaralı kemik kisti"]}},"xrefs":[{"source":"ICD-10","code":"M85.4","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"FB80.5","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"987501456"},{"source":"MONDO","code":"0019372","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0005937","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93419,"name":"Rare bone disease"},"parents":[{"orpha":68411,"name":"Rare bone tumor","classifications":[199,202]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Childhood"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2019-06-06","source":"27075249[PMID]_27554346[PMID]_30691312[PMID]_30726590[PMID]_30969659[PMID]_30969671[PMID]","terms":[{"hpo":"HP:0012064","label":"Unicameral bone cyst","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0003926","label":"Abnormality of the humeral diaphysis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0100253","label":"Abnormality of the medullary cavity of the long bones","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002653","label":"Bone pain","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002756","label":"Pathologic fracture","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0006431","label":"Proximal femoral metaphyseal abnormality","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002992","label":"Abnormality of tibia morphology","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012428","label":"Prominent calcaneus","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0003312","label":"Abnormal form of the vertebral bodies","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0002696","label":"Abnormal parietal bone morphology","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0002867","label":"Abnormality of the ilium","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0000707","label":"Abnormality of the nervous system","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0003172","label":"Abnormality of the pubic bone","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0002143","label":"Abnormality of the spinal cord","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0003418","label":"Back pain","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0003979","label":"Lytic defects of the radius","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0100748","label":"Muscular edema","frequency":"Very rare (<4-1%)","criteria":null}]}}