{"orpha":83317,"name":"Scrub typhus","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Tsutsugamushi disease","Tsutsugamushi fever"],"definition":"Scrub typhus is a rare dust mite-borne infectious disease caused by the <i>Orientia tsutsugamushi</i> bacterium and characterized clinically by an eruptive fever which is potentially serious.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-83317/","orphanet_url":"https://www.orpha.net/en/disease/detail/83317","names":{"fr":{"name":"Typhus des broussailles","synonyms":["Fièvre de Tsutsugamushi","Fièvre fluviale du Japon","Maladie de Tsutsugamushi"],"definition":"Le typhus des broussailles est une maladie infectieuse rare causée par la bactérie <i>Orientia tsutsugamushi</i> et transmise par la piqûre d'acariens thrombiculidés, elle est caractérisée par une fièvre éruptive potentiellement grave."},"de":{"name":"Scrub-Typhus","synonyms":["Tsutsugamushi-Fieber","Tsutsugamushi-Krankheit"],"definition":"Der Scrub-Typhus (<i>scrub</i> = Buschwerk) ist eine seltene, von Milben übertragene Infektion mit dem Bakterium <i>Orientia tsutsugamushi</i>. Kennzeichnend ist das akut einsetzende, potenziell schwere Fieber."},"es":{"name":"Tifus de las malezas","synonyms":["Enfermedad de Tsutsugamushi","Fiebre de Tsutsugamushi"],"definition":"La fiebre de los matorrales (o fiebre de Tsutsumagushi o tifus de los matorrales o tifus de las malezas) es una enfermedad infecciosa poco frecuente transmitida por los ácaros del polvo y causada por la bacteria <i>Orientia tsutsugamushi</i> que se caracteriza clínicamente por una fiebre eruptiva potencialmente grave."},"it":{"name":"Tifo da acari","synonyms":["Febbre di Tsutsugamushi","Malattia di Tsutsugamushi"],"definition":"Il tifo da acari è una malattia infettiva rara causata dagli acari della polvere (batterio <i>Orientia tsutsugamushi</i>); è caratterizzata da febbre eruttiva potenzialmente grave."},"nl":{"name":"Scrubtyfus","synonyms":["Infectie door Orientia tsutsugamushi","Tsutsugamushi-koorts","Tsutsugamushi-ziekte"],"definition":"Scrubtyfus is een zeldzame infectieziekte, overgedragen door oogstmijten, die wordt veroorzaakt door de <i>Orientia tsutsugamushi</i>-bacterie en die klinisch gekenmerkt wordt door een eruptieve koorts die potentieel ernstig is."},"pt":{"name":"Tifo dos arbustos","synonyms":["Doença de Tsutsugamushi","Febre de Tsutsugamushi"]},"pl":{"name":"Japońska gorączka rzeczna","synonyms":["Choroba tsutsugamushi","Gorączka tsutsugamushi"]},"cs":{"name":"Křovinný tyfus","synonyms":["Nemoc tsutsugamushi","Horečka tsutsugamushi","Japonská říční horečka"]},"uk":{"name":"Скрабовий висипний тиф","synonyms":["Хвороба Цуцугамуші","Лихоманка Цуцугамуші"],"definition":"Scrub typhus is a rare dust mite-borne infectious disease caused by the <i>Orientia tsutsugamushi</i> bacterium and characterized clinically by an eruptive fever which is potentially serious."},"zh":{"name":"恙虫热斑疹伤寒","synonyms":["恙虫病"]},"tr":{"name":"Scrub tifüs","synonyms":["Tsutsugamushi ateşi","Tsutsugamushi hastalığı"]}},"xrefs":[{"source":"ICD-10","code":"A75.3","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"1C30.3","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1695340384"},{"source":"MONDO","code":"0019365","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D012612","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0036472","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10039766","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":163582,"name":"Rare bacterial infectious disease","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 100 000","value":7.2,"area":"Korea, Republic of","status":"Validated","source":"18362409[PMID]"},{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.3,"area":"Japan","status":"Validated","source":"18362409[PMID]"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2016-06-01","source":null,"terms":[{"hpo":"HP:0012735","label":"Cough","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001945","label":"Fever","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0000975","label":"Hyperhidrosis","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001254","label":"Lethargy","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0003326","label":"Myalgia","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0004372","label":"Reduced consciousness","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0000988","label":"Skin rash","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0002027","label":"Abdominal pain","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0012122","label":"Anterior uveitis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0100758","label":"Gangrene","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002315","label":"Headache","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002615","label":"Hypotension","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002716","label":"Lymphadenopathy","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0012733","label":"Macule","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002017","label":"Nausea and vomiting","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000613","label":"Photophobia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001892","label":"Abnormal bleeding","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000708","label":"Atypical behavior","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002094","label":"Dyspnea","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002383","label":"Infectious encephalitis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001287","label":"Meningitis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012819","label":"Myocarditis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000083","label":"Renal insufficiency","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002091","label":"Restrictive ventilatory defect","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001250","label":"Seizure","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001744","label":"Splenomegaly","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001337","label":"Tremor","frequency":"Occasional (29-5%)","criteria":null}]}}