{"orpha":83316,"name":"Pseudotyphus of California","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"Pseudotyphus of California is a rare, flea-borne Rickettsial disease caused by a <i>Rickettsia felis </i> infection. Patients can be asymptomatic or can present with unspecific symptoms (such as fever, headache, generalized maculopapular rash, myalgia, arthralgia and, ocasionally, eschar, lymphadenopathy, nausea, vomiting, loss of appetite and abdominal pain). Rarely, serious manifestations may occur and include neurological dysfunction (photophobia, hearing loss, and signs of meningitis) and pulmonary compromise.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-83316/","orphanet_url":"https://www.orpha.net/en/disease/detail/83316","names":{"fr":{"name":"Pseudotyphus de la Californie","definition":"Le pseudotyphus de la Californie est une rickettsiose à puce rare, causée par une infection par <i>Rickettsia felis</i>. Les patients peuvent être asymptomatiques ou peuvent présenter des signes non spécifiques (fièvre, céphalées, éruption maculopapuleuse généralisée, myalgie, arthralgie et parfois, escarres, lymphadénopathie, nausées, vomissements, perte d'appétit et douleur abdominale). Des manifestations graves peuvent survenir dans de rares cas, et incluent une dysfonction neurologique (photophobie, perte auditive, signes de méningite) et une insuffisance pulmonaire."},"de":{"name":"Pseudotyphus California","definition":"Pseudotyphus of California ist eine seltene, durch Flöhe übertragene Rickettsien-Krankheit, die durch eine <i>Rickettsia felis </i>-Infektion verursacht wird. Die Patienten können asymptomatisch sein oder sich mit unspezifischen Symptomen präsentieren (wie Fieber, Kopfschmerzen, generalisierter makulopapulöser Ausschlag, Myalgie, Arthralgie und gelegentlich Schorf, Lymphadenopathie, Übelkeit, Erbrechen, Appetitlosigkeit und Bauchschmerzen). Selten können schwerwiegende Manifestationen auftreten, zu denen neurologische Funktionsstörungen (Photophobie, Hörverlust und Anzeichen einer Meningitis) und pulmonale Beeinträchtigungen gehören."},"es":{"name":"Pseudotifus de Califonia","definition":"El pseudotifus de California es una enfermedad poco frecuente. Esta infección es transmitida por pulgas y causada por <i> Rickettsia felis </ i>. Los afectados pueden ser asintomáticos o presentar síntomas inespecíficos (tales como fiebre, dolor de cabeza, erupción maculopapular generalizada, mialgias, artralgias y, ocasionalmente, escaras, linfadenopatía, náuseas, vómitos, pérdida de apetito y dolor abdominal). En raras ocasiones, pueden presentarse manifestaciones graves que incluyen disfunción neurológica (fotofobia, pérdida de audición y signos de meningitis) y compromiso pulmonar."},"it":{"name":"Pseudotifo della California","definition":"Lo pseuditifo della California è una rickettsiosi trasmessa dalle pulci, causata da un'infezione da Rickettsia felis. I pazienti possono essere asintomatici oppure presentare sintomi aspecifici (febbre, cefalea, eritema maculo-papulare generalizzato, mialgia, artralgia e, raramente, escara, linfoadenopatia, nausea, vomito, perdita dell'appetito e dolore addominale). Raramente si manifestano segni clinici gravi, come la disfunzione neurologica (fotofobia, sordità e segni della meningite) e la compromissione polmonare."},"nl":{"name":"Pseudotyfus van Californië","definition":"Pseudotyfus van Californië is een zeldzame, door vlooien overgedragen Rickettsiose veroorzaakt door een infectie met <i>Rickettsia felis </i>. Patiënten kunnen asymptomatisch zijn of niet-specifieke symptomen vertonen (zoals koorts, hoofdpijn, gegeneraliseerde maculopapulaire uitslag, myalgie, artralgie en, soms, eschar, lymfadenopathie, misselijkheid, braken, verlies van eetlust en buikpijn). In zeldzame gevallen kunnen ernstige manifestaties voorkomen, waaronder neurologische dysfunctie (fotofobie, gehoorverlies, en tekenen van meningitis) en pulmonale complicaties."},"pt":{"name":"Pseudo-tifo da Califórnia"},"pl":{"name":"Pseudotyfus kalifornijski"},"cs":{"name":"Kalifornský pseudotyfus"},"uk":{"name":"Псевдотиф каліфорнійський","definition":"Pseudotyphus of California is a rare, flea-borne Rickettsial disease caused by a <i>Rickettsia felis </i> infection. Patients can be asymptomatic or can present with unspecific symptoms (such as fever, headache, generalized maculopapular rash, myalgia, arthralgia and, ocasionally, eschar, lymphadenopathy, nausea, vomiting, loss of appetite and abdominal pain). Rarely, serious manifestations may occur and include neurological dysfunction (photophobia, hearing loss, and signs of meningitis) and pulmonary compromise."},"zh":{"name":"加州假斑疹伤寒"},"tr":{"name":"Kaliforniya psödotifüsü"}},"xrefs":[{"source":"ICD-10","code":"A79.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"1C30.Y","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0019364","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4706680","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":102022,"name":"Spotted fever rickettsiosis","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}