{"orpha":79098,"name":"Sympathetic ophthalmia","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Sympathetic uveitis"],"definition":"Sympathetic ophthalmia (SO) is a bilateral granulomatous anterior uveitis usually occurring within the three months following trauma or a surgical procedure involving one eye.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-79098/","orphanet_url":"https://www.orpha.net/en/disease/detail/79098","names":{"fr":{"name":"Ophtalmie sympathique","synonyms":["Uvéite sympathique"],"definition":"L'ophtalmie sympathique (OS) est une uvéite antérieure granulomateuse bilatérale survenant habituellement dans les trois mois après un traumatisme ou une intervention chirurgicale intéressant l'un des yeux."},"de":{"name":"Sympathische Ophthalmie","synonyms":["Uveitis, sympathische"],"definition":"Die Ophthalmia sympathica (SO) ist eine beidseitige granulierende anteriore Uveitis, die meist innerhalb von drei Monaten nach Trauma oder chirurgischem Eingriff an einem der beiden Augen auftritt."},"es":{"name":"Oftalmia simpática","synonyms":["Uveítis simpática"],"definition":"La oftalmia simpática (OS) es una uveitis anterior granulomatosa bilateral que suele aparecer en los tres meses posteriores a un trauma o a una operación quirúrgica en el ojo."},"it":{"name":"Oftalmia simpatica","synonyms":["Uveite simpatica"]},"nl":{"name":"Sympathische oftalmie","synonyms":["Sympathische uveïtis"],"definition":"Sympathische oftalmie (SO) is een bilaterale granulomateuze anterieure uveïtis die meestal optreedt binnen de drie maanden na trauma of chirurgische procedure met betrokkenheid van één oog."},"pt":{"name":"Oftalmia simpática","definition":"A oftalmia simpática (SO) é uma uveíte granulomatosa anterior bilateral que ocorre habitualmente nos três meses após traumatismo ou procedimento cirúrgico envolvendo um olho."},"pl":{"name":"Oftalmia współczulna","synonyms":["Współczulne zapalenie błony naczyniowej"]},"cs":{"name":"Sympatická oftalmie","synonyms":["Sympatická uveitida"]},"uk":{"name":"Симпатична офтальмія","synonyms":["Симпатичний увеїт"],"definition":"Sympathetic ophthalmia (SO) is a bilateral granulomatous anterior uveitis usually occurring within the three months following trauma or a surgical procedure involving one eye."},"zh":{"name":"交感性眼炎","synonyms":["交感性眼炎"]},"tr":{"name":"Sempatik oftalmi","synonyms":["Sempatik üveit"]}},"xrefs":[{"source":"ICD-10","code":"H44.1","qualifier":"NTBT","icd_relation":"inclusion","validated":true},{"source":"ICD-11","code":"9B65.0","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1639718137"},{"source":"MONDO","code":"0019198","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D009879","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0029077","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10042742","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97966,"name":"Rare ophthalmic disorder"},"parents":[{"orpha":306648,"name":"Non-infectious anterior uveitis","classifications":[189]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.03,"area":"United Kingdom","status":"Validated","source":"10684834[PMID]"},{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.6,"area":"Europe","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2023-03-23","source":"33256432[PMID]_30959067[PMID]_30207811[PMID]","terms":[{"hpo":"HP:0007663","label":"Reduced visual acuity","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0025560","label":"Anterior chamber cells","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000518","label":"Cataract","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0025341","label":"Corneal keratic precipitates","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000501","label":"Glaucoma","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000541","label":"Retinal detachment","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0030823","label":"Scleral thickening","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0011531","label":"Vitritis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001596","label":"Alopecia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:6000710","label":"Dalen Fuchs nodules","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0007680","label":"Depigmented fundus","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0010783","label":"Erythema","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002315","label":"Headache","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000365","label":"Hearing impairment","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0040049","label":"Macular edema","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0007906","label":"Ocular hypertension","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0200026","label":"Ocular pain","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001085","label":"Papilledema","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000613","label":"Photophobia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002290","label":"Poliosis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0011484","label":"Posterior synechiae of the anterior chamber","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012123","label":"Posterior uveitis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000573","label":"Retinal hemorrhage","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000360","label":"Tinnitus","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001045","label":"Vitiligo","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100832","label":"Vitreous floaters","frequency":"Occasional (29-5%)","criteria":null}]}}