{"orpha":73423,"name":"Acute ackee fruit intoxication","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Acute intoxication by Blighia sapida","Jamaican vomiting sickness","Jamaican vomiting syndrome"],"definition":"A rare disorder due to poisoning caused by the ingestion of unripe Blighia sapida fruits, clinically characterized by toxic hypoglycaemia and inhibition of neoglucogenesis.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-73423/","orphanet_url":"https://www.orpha.net/en/disease/detail/73423","names":{"fr":{"name":"Intoxication aiguë par le fruit d'aki","synonyms":["Intoxication aiguë par Blighia sapida","Intoxication aiguë par le fruit d'akée","Maladie des vomissements de la Jamaïque","Maladie émétisante jamaïcaine"],"definition":"Maladie rare due à une intoxication provoquée par l'ingestion de fruits non mûrs de <i>Blighia sapida</i>, caractérisée sur le plan clinique par une hypoglycémie toxique et par l'inhibition de la néoglucogenèse."},"de":{"name":"Akee-Frucht-Vergiftung, akute","synonyms":["Akute Vergiftung durch Blighia sapida","Blighia sapida (Akeepflaume), akute Vergiftung","Jamaika-Brechkrankheit"],"definition":"Eine seltene Vergiftungserkrankung, die durch den Verzehr unreifer Früchte der 'Akipflaume' <i>Blighia sapida</i> verursacht wird und klinisch durch toxische Hypoglykämie und Hemmung der Neoglukogenese gekennzeichnet ist."},"es":{"name":"Intoxicación aguda por fruto de ackee","synonyms":["Enfermedad jamaicana del vómito","Intoxicación aguda por Blighia sapida","Intoxicación aguda por seso vegetal","Síndrome jamaicano del vómito"],"definition":"Es un trastorno poco frecuente debido a la intoxicación causada por la ingestión de frutos inmaduros de Blighia sapida. Clínicamente se caracteriza por hipoglucemia tóxica e inhibición de la neoglucogénesis."},"it":{"name":"Intossicazione acuta da frutto ackee","synonyms":["Intossicazione acuta da Blighia sapida","Malattia del vomito della Giamaica","Sindrome del vomito della Giamaica"]},"nl":{"name":"Acute Akivruchtintoxicatie","synonyms":["Acute intoxicatie door Blighia sapida","Jamaicaans braaksyndroom","Jamaicaanse braakziekte"],"definition":"Een zeldzame aandoening door vergiftiging veroorzaakt door inname van onrijp fruit van Blighia sapida, klinisch gekenmerkt door toxische hypoglycemie en inhibitie van gluconeogenese."},"pt":{"name":"Intoxicação aguda por fruta ackee","synonyms":["Doença do vómito da Jamaica","Intoxicação aguda por Blighia sapida","Síndrome do vómito da Jamaica"],"definition":"Doença rara devida ao envenenamento causado pela ingestão de frutos verdes de Blighia sapida, clinicamente caracterizado por hipoglicemia tóxica e inibição da neoglicogénese."},"pl":{"name":"Ostre zatrucie owocem ackee","synonyms":["Jamajska choroba wymiotna","Jamajski zespół wymiotów","Ostre zatrucie Bligią pospolitą"]},"cs":{"name":"Akutní intoxikace ovocem ackee","synonyms":["Akutní intoxikace ovocem akee","Akutní intoxikace Blighia sapida","Jamajská nemoc zvracení","Jamajský syndrom zvracení"]},"uk":{"name":"Гостра інтоксикація плодами алое","synonyms":["Гостра інтоксикація Blighia sapida","Ямайська блювотна хвороба","Синдром ямайської блювоти"],"definition":"A rare disorder due to poisoning caused by the ingestion of unripe Blighia sapida fruits, clinically characterized by toxic hypoglycaemia and inhibition of neoglucogenesis."},"zh":{"name":"急性西非荔枝果中毒","synonyms":["西非荔枝果急性中毒"]},"tr":{"name":"Akut ake meyve zehirlenmesi","synonyms":["Jamaika kusma hastalığı","Jamaika kusma sendromu","Blighia sapida tarafından akut zehirlenme"]}},"xrefs":[{"source":"ICD-10","code":"T62.2","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"NE61","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0019140","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0274888","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"9299","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":108999,"name":"Rare disorder due to toxic effects"},"parents":[{"orpha":556508,"name":"Rare disorder due to poisoning","classifications":[204]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":null}