{"orpha":730672,"name":"Isolated complex neurodevelopmental disorder without intellectual disability or autism spectrum disorder","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare neurodevelopmental disorder characterized by the combination of at least two neurodevelopmental disorders, including specific learning disorder (e.g., impairment in reading, written expression, or mathematics), motor disorder (e.g. developmental coordination disorder, stereotypic movement disorder, tic disorder), communication disorder (e.g., developmental language disorder, speech sound disorder, childhood-onset fluency disorder, social/pragmatic communication disorder), attention deficit/hyperactivity disorder (ADD/ADHD) and other specified or unspecified neurodevelopmental disorders as defined in DSM-5 or ICD-11. Patients don't reach the criteria of an autism spectrum disorder diagnosis, do not have intellectual disability or any dysmorphic features or congenital anomalies.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-730672/","orphanet_url":"https://www.orpha.net/en/disease/detail/730672","names":{"fr":{"name":"Trouble complexe du neurodéveloppement isolé sans déficience intellectuelle ni trouble du spectre autistique","definition":"Trouble du neurodéveloppement rare caractérisé par l'association d'au moins deux troubles du neurodéveloppement, notamment d'un trouble spécifique des apprentissages (par exemple, des difficultés en lecture, en expression écrite ou en mathématiques), d'un trouble moteur (par exemple, le trouble développemental de la coordination, le trouble des mouvements stéréotypés, le trouble des tics), d'un trouble de la communication (par exemple, les troubles du langage oral, le trouble des sons de la parole, le trouble de la fluidité d'apparition infantile, le trouble de la communication sociale/pragmatique), d'un trouble du déficit de l'attention/hyperactivité (TDA/TDAH) et d'autres troubles neurodéveloppementaux spécifiés ou non spécifiés tels que définis dans les classifications DSM-5 ou CIM-11. Les patients ne répondent pas aux critères de diagnostic d'un trouble du spectre de l'autisme, ne présentent pas de déficience intellectuelle, de dysmorphie ni d'anomalies congénitales."},"de":{"name":"Isolierte komplexe neurologische Entwicklungsstörung ohne Intelligenzminderung oder Autismus-Spektrum-Störung","synonyms":["Isolierte komplexe neurologische Entwicklungsstörung ohne IM oder ASS"]},"es":{"name":"Trastorno del neurodesarrollo complejo aislado sin discapacidad intelectual ni trastorno del espectro autista"},"it":{"name":"Disturbo neuroevolutivo complesso isolato, senza disabilità intellettiva o disturbo dello spettro autistico"},"nl":{"name":"Geïsoleerde complexe neurologische ontwikkelingsstoornis zonder intellectuele achterstand of autismespectrumstoornis"},"pt":{"name":"Isolated complex neurodevelopmental disorder without intellectual disability or autism spectrum disorder"},"pl":{"name":"Isolated complex neurodevelopmental disorder without intellectual disability or autism spectrum disorder"},"cs":{"name":"Isolated complex neurodevelopmental disorder without intellectual disability or autism spectrum disorder"}},"xrefs":[],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":730693,"name":"Rare complex neurodevelopmental disorder without intellectual disability or autism spectrum disorder","classifications":[156,181]}],"children":[{"orpha":730675,"name":"Isolated complex neurodevelopmental disorder without ID/ASD of genetic/genomic origin","type":"Etiological subtype"},{"orpha":730679,"name":"Isolated complex neurodevelopmental disorder without ID/ASD of not yet identified genetic/genomic cause","type":"Etiological subtype"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}