{"orpha":718053,"name":"Combined immunodeficiency with low CD4 and normal CD8","type":"Clinical group","group":"Group of disorders","status":"active","flags":[],"synonyms":["CID with low CD4 and normal CD8"],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-718053/","orphanet_url":"https://www.orpha.net/en/disease/detail/718053","names":{"fr":{"name":"Déficit immunitaire combiné avec CD4 faibles et CD8 normaux","synonyms":["CID avec CD4 faibles et CD8 normaux","DIC avec CD4 faibles et CD8 normaux","Immunodéficience combinée avec CD4 faibles et CD8 normaux"]},"de":{"name":"Kombinierter Immundefekt mit niedrigem CD4- und normalem CD8-Wert","synonyms":["CID mit niedrigem CD4- und normalem CD8-Wert"]},"es":{"name":"Inmunodeficiencia combinada con niveles bajos de CD4 y niveles normales de CD8","synonyms":["CID con niveles bajos de CD4 y niveles normales de CD8","IDC con niveles bajos de CD4 y niveles normales de CD8"]},"it":{"name":"Immunodeficienza combinata con livelli bassi di CD4 e livelli normali di CD8","synonyms":["CID con livelli bassi di CD4 e livelli normali di CD8"]},"nl":{"name":"Gecombineerde immuundeficiëntie met laag CD4 en normaal CD8","synonyms":["CID met laag CD4 en normaal CD8"]},"pt":{"name":"Combined immunodeficiency with low CD4 and normal CD8"},"pl":{"name":"Combined immunodeficiency with low CD4 and normal CD8","synonyms":["CID with low CD4 and normal CD8"]},"cs":{"name":"Combined immunodeficiency with low CD4 and normal CD8","synonyms":["CID with low CD4 and normal CD8"]}},"xrefs":[{"source":"ICD-10","code":"D81.8","qualifier":"NTBT","icd_relation":"attributed","validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98004,"name":"Rare immune disease"},"parents":[{"orpha":480549,"name":"Non-severe combined immunodeficiency","classifications":[156,195,233]}],"children":[{"orpha":538963,"name":"Combined immunodeficiency due to ITK deficiency","type":"Disease"},{"orpha":280142,"name":"Combined immunodeficiency due to LCK deficiency","type":"Disease"},{"orpha":314689,"name":"Combined immunodeficiency due to STK4 deficiency","type":"Disease"},{"orpha":718047,"name":"Combined immunodeficiency due to polymerase delta deficiency","type":"Disease"},{"orpha":34592,"name":"Immunodeficiency by defective expression of MHC class I","type":"Disease"},{"orpha":572,"name":"Immunodeficiency by defective expression of MHC class II","type":"Disease"},{"orpha":169105,"name":"Thymoma-hypogammaglobulinemia syndrome","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}