{"orpha":715025,"name":"Spinal fast-flow vascular malformation","type":"Clinical group","group":"Group of disorders","status":"active","flags":[],"synonyms":["Spinal arteriovenous malformation","Spinal arteriovenous shunt"],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-715025/","orphanet_url":"https://www.orpha.net/en/disease/detail/715025","names":{"fr":{"name":"Malformation vasculaire spinale à flux rapide","synonyms":["Malformation artérioveineuse spinale"]},"de":{"name":"Spinale schnell-fließende vaskuläre Fehlbildung","synonyms":["Spinale arteriovenöse Gefäßmalformation","Spinale arteriovenöse fast-flow Malformation","Spinale Gefäßmalformation mit arteriovenösem Shunt"]},"es":{"name":"Malformación vascular espinal de alto flujo","synonyms":["Malformación arteriovenosa espinal","Derivación arteriovenosa espinal"]},"it":{"name":"Malformazione vascolare spinale a flusso rapido","synonyms":["Malformazione arterovenosa spinale","Shunt arterovenoso spinale"]},"nl":{"name":"Spinale fast-flow vasculaire malformatie","synonyms":["Spinale arterioveneuze malformatie","Spinale arterioveneuze fistel","Spinale arterioveneuze shunt","Vaatmalformatie van ruggenmerg met snelle bloedstroom"]},"pt":{"name":"Spinal fast-flow malformation"},"pl":{"name":"Malformacja rdzenia kręgowego z szybkim przepływem","synonyms":["Spinal arteriovenous malformation","Spinal arteriovenous shunt"]},"cs":{"name":"Spinal fast-flow vascular malformation","synonyms":["Spinal arteriovenous malformation","Spinal arteriovenous shunt"]}},"xrefs":[],"associations":[],"incoming_associations":[{"type":"Referred to","orpha":79093,"name":"OBSOLETE: Foix-Alajouanine syndrome","status":"inactive"}],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":715744,"name":"Fast-flow vascular malformation of the central nervous system","classifications":[147,198]},{"orpha":102006,"name":"Neurovascular malformation","classifications":[181]}],"children":[{"orpha":715307,"name":"Acquired spinal dural arteriovenous fistula","type":"Morphological anomaly"},{"orpha":720027,"name":"Late-onset spinal arteriovenous fistula","type":"Morphological anomaly"},{"orpha":720023,"name":"Neonatal/infantile-onset spinal arteriovenous fistula","type":"Malformation syndrome"},{"orpha":715331,"name":"Paraspinal arteriovenous malformation","type":"Morphological anomaly"},{"orpha":715284,"name":"Spinal cord arteriovenous malformation, nidus type","type":"Morphological anomaly"},{"orpha":715326,"name":"Spinal epidural arteriovenous malformation","type":"Morphological anomaly"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2025-10-14","source":"34178190[PMID]_28673891[PMID]_33457368[PMID]","terms":[{"hpo":"HP:0012703","label":"Abnormal subarachnoid space morphology","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0000707","label":"Abnormality of the nervous system","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0004947","label":"Arteriovenous fistula","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0040272","label":"Hyperintensity of MRI T2 signal of the spinal cord","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0002196","label":"Myelopathy","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0100561","label":"Spinal cord lesion","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0012721","label":"Venous malformation","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001284","label":"Areflexia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0003418","label":"Back pain","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001347","label":"Hyperreflexia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001324","label":"Muscle weakness","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0012486","label":"Myelitis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0007199","label":"Progressive spastic paraparesis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002607","label":"Bowel incontinence","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012423","label":"Colonic inertia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0009053","label":"Distal lower limb muscle weakness","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012534","label":"Dysesthesia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0030014","label":"Female sexual dysfunction","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002359","label":"Frequent falls","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000009","label":"Functional abnormality of the bladder","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001288","label":"Gait disturbance","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002141","label":"Gait imbalance","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0003419","label":"Low back pain","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0007340","label":"Lower limb muscle weakness","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0040307","label":"Male sexual dysfunction","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000011","label":"Neurogenic bladder","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0003401","label":"Paresthesia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0003474","label":"Somatic sensory dysfunction","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002317","label":"Unsteady gait","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000020","label":"Urinary incontinence","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000016","label":"Urinary retention","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002318","label":"Cervical myelopathy","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0008944","label":"Distal lower limb amyotrophy","frequency":"Very rare (<4-1%)","criteria":null}]}}