{"orpha":700090,"name":"Sickle cell S-O Arab disease","type":"Clinical subtype","group":"Subtype of disorder","status":"active","flags":[],"synonyms":["HbS-O Arab disease","Hemoglobin S-O Arab disease"],"definition":null,"note":null,"url":"https://raremap.alftech.space/d/ORPHA-700090/","orphanet_url":"https://www.orpha.net/en/disease/detail/700090","names":{"fr":{"name":"Drépanocytose S-O Arab","synonyms":["Hémoglobinose S-O Arab"]},"de":{"name":"Sichelzellkrankheit S-Arab","synonyms":["HbSOArab","Hämoglobin S-O Arab","SCD-S/OArab"]},"es":{"name":"Anemia falciforme SO-árabe","synonyms":["Anemia HbSO-árabe","Anemia de células falciformes SO-árabe","Enfermedad de la hemoglobina SO-árabe"]},"it":{"name":"Falcemia S-O araba","synonyms":["Malattia HbS-O araba","Malattia correlata all’emoglobina S-O araba"]},"nl":{"name":"Sikkelcelziekte door HbS-O-Arab","synonyms":["Sikkelcelziekte door hemoglobine S-O-Arab"]},"pt":{"name":"Sickle cell S-O Arab disease"},"pl":{"name":"Sickle cell S-O Arab disease","synonyms":["HbS-O Arab disease","Hemoglobin S-O Arab disease"]},"cs":{"name":"Sickle cell S-O Arab disease","synonyms":["HbS-O Arab disease","Hemoglobin S-O Arab disease"]}},"xrefs":[],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97992,"name":"Rare hematologic disease"},"parents":[{"orpha":700085,"name":"Sickle cell disease due to hemoglobin S and a non-S/non-C hemoglobin variant","classifications":[156,194,233]}],"children":[],"genes":[{"symbol":"HBB","name":"hemoglobin subunit beta","gene_type":"gene with protein product","association":"Disease-causing germline mutation(s) in","status":"Assessed","source":"32595482[PMID]","hgnc":"4827","ensembl":"ENSG00000244734","omim":"141900","loci":["11p15.4"]}],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}