{"orpha":694963,"name":"Inflammatory breast cancer","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["IBC","ICB","Inflammatory carcinoma of the breast","Mastitis carcinomatosa"],"definition":null,"note":null,"url":"https://raremap.alftech.space/d/ORPHA-694963/","orphanet_url":"https://www.orpha.net/en/disease/detail/694963","names":{"fr":{"name":"Cancer inflammatoire du sein","synonyms":["Mastite carcinomateuse"]},"de":{"name":"Brustkrebs, inflammatorischer","synonyms":["IBC","ICB","Inflammatorisches Karzinom der Brust","Karzinomatöse Mastitis"]},"es":{"name":"Cáncer de mama inflamatorio","synonyms":["CMI","Carcinoma de mama inflamatorio","IBC","ICB","Mastitis carcinomatosa"]},"it":{"name":"Tumore infiammatorio della mammella","synonyms":["Mastite carcinomatosa","IBC","ICB","Carcinoma infiammatorio della mammella"]},"nl":{"name":"Inflammatoire borstkanker","synonyms":["IBC","ICB","Inflammatoir carcinoom van borst","Mastitis carcinomatosa"]},"pt":{"name":"Inflammatory breast cancer"},"pl":{"name":"Inflammatory breast cancer","synonyms":["IBC","ICB","Inflammatory carcinoma of the breast","Mastitis carcinomatosa"]},"cs":{"name":"Inflammatory breast cancer","synonyms":["IBC","ICB","Inflammatory carcinoma of the breast","Mastitis carcinomatosa"]}},"xrefs":[{"source":"ICD-10","code":"C50.9","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"2C62","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"986359233"}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":180257,"name":"Rare malignant breast tumor","classifications":[202,205]}],"children":[],"genes":[{"symbol":"BRCA1","name":"BRCA1 DNA repair associated","gene_type":"gene with protein product","association":"Major susceptibility factor in","status":"Assessed","source":"34445631[PMID]","hgnc":"1100","ensembl":"ENSG00000012048","omim":"113705","loci":["17q21.31"]},{"symbol":"BRCA2","name":"BRCA2 DNA repair associated","gene_type":"gene with protein product","association":"Major susceptibility factor in","status":"Assessed","source":"34445631[PMID]","hgnc":"1101","ensembl":"ENSG00000139618","omim":"600185","loci":["13q13.1"]}],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adult","Elderly"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":2.5,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":null}