{"orpha":688571,"name":"Combined immunodeficiency with low immunoglobulins and normal B cells","type":"Clinical group","group":"Group of disorders","status":"active","flags":[],"synonyms":["CID with low Ig and normal B cells","Combined immunodeficiency low Ig and normal B cells"],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-688571/","orphanet_url":"https://www.orpha.net/en/disease/detail/688571","names":{"fr":{"name":"Déficit immunitaire combiné avec immunoglobulines faibles et cellules B normales","synonyms":["CID avec Ig faibles et cellules B normales","DIC avec Ig faibles et cellules B normales","Immunodéficience combinée avec Ig faibles et cellules B normales"]},"de":{"name":"Kombinierter Immundefekt mit niedrigen Immunglobulin-Werten und normalen B-Zellen","synonyms":["CID mit niedrigen Ig und normalen B-Zellen","Kombinierter Immundefekt mit niedrigem Ig-Spiegel und normalen B-Zellen"]},"es":{"name":"Inmunodeficiencia combinada con niveles bajos de inmunoglobulinas y normales de células B","synonyms":["IDC con niveles bajos de Ig y normales de células B","CID con niveles bajos de Ig y normales de células B","Inmunodeficiencia combinada con niveles bajos de Ig y normales de células B"]},"it":{"name":"Immunodeficienza combinata grave con livelli bassi di immunoglobuline e livelli normali di cellule B","synonyms":["CID con livelli bassi di Ig e livelli normali di cellule B","Immunodeficienza combinata grave con livelli bassi di Ig e livelli normali di cellule B"]},"nl":{"name":"Gecombineerde immuundeficiëntie met lage immunoglobulinen en normale B-cellen","synonyms":["CID met lage Ig en normale B-cellen","Gecombineerde immuundeficiëntie met lage Ig en normale B-cellen"]},"pt":{"name":"Imunodeficiência combinada com diminuição de imunoglobulinas","synonyms":["CID com diminuição de Ig","Imunodeficiência combinada diminuição de Ig"]},"pl":{"name":"Skojarzony niedobór odporności z niskiem poziomem immunoglobulin","synonyms":["CID with low Ig and normal B cells","Combined immunodeficiency low Ig and normal B cells"]},"cs":{"name":"Kombinovaná imunodeficience s nízkou hladinou imunoglobulinů","synonyms":["CID with low Ig and normal B cells","Combined immunodeficiency low Ig and normal B cells"]}},"xrefs":[],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98004,"name":"Rare immune disease"},"parents":[{"orpha":480549,"name":"Non-severe combined immunodeficiency","classifications":[156,195,233]}],"children":[{"orpha":357237,"name":"Combined immunodeficiency due to CARD11 deficiency","type":"Disease"},{"orpha":447737,"name":"Combined immunodeficiency due to DOCK2 deficiency","type":"Disease"},{"orpha":697389,"name":"Combined immunodeficiency due to HELIOS deficiency","type":"Disease"},{"orpha":397787,"name":"Combined immunodeficiency due to IKBKB deficiency","type":"Disease"},{"orpha":357329,"name":"Combined immunodeficiency due to IL21R deficiency","type":"Disease"},{"orpha":723161,"name":"Combined immunodeficiency due to NFATC1 deficiency","type":"Disease"},{"orpha":476113,"name":"Combined immunodeficiency due to TFRC deficiency","type":"Disease"},{"orpha":697394,"name":"Combined immunodeficiency due to c-REL deficiency","type":"Disease"},{"orpha":726452,"name":"Combined immunodeficiency with early gray hairing","type":"Disease"},{"orpha":699578,"name":"Combined immunodeficiency with low Ig due to BCL10 deficiency","type":"Disease"},{"orpha":697385,"name":"Combined immunodeficiency-cancer predisposing syndrome due to AIOLOS deficiency","type":"Disease"},{"orpha":697403,"name":"Combined immunodeficiency-hypogammaglobulinemia-skeletal anomalies syndrome due to IKBKA deficiency","type":"Disease"},{"orpha":697414,"name":"Early-onset combined immunodeficiency with low Ig due to dominant negative IKAROS mutation","type":"Disease"},{"orpha":183663,"name":"Hyper-IgM syndrome with susceptibility to opportunistic infections","type":"Disease"},{"orpha":695183,"name":"Late-onset combined immunodeficiency due to ICOS deficiency","type":"Disease"},{"orpha":695191,"name":"Late-onset combined immunodeficiency due to ICOSL deficiency","type":"Disease"},{"orpha":692812,"name":"RAC2-related combined immunodeficiency-bronchiectasis-cancer-predisposing syndrome","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}