{"orpha":687730,"name":"Unifocal Langerhans cell histiocytosis","type":"Clinical subtype","group":"Subtype of disorder","status":"active","flags":[],"synonyms":["Unifocal Langerhans cell granulomatosis","Unifocal histiocytosis X"],"definition":null,"note":null,"url":"https://raremap.alftech.space/d/ORPHA-687730/","orphanet_url":"https://www.orpha.net/en/disease/detail/687730","names":{"fr":{"name":"Histiocytose langerhansienne unifocale","synonyms":["Granulomatose à cellules de Langerhans unifocale","Histiocytose X unifocale"]},"de":{"name":"Langerhans-Zell-Histiozytose, unifokale","synonyms":["Histiozytose X, unifokale","Langerhans-Zell-Granulomatose, unifokale"]},"es":{"name":"Histiocitosis de células de Langerhans unifocal","synonyms":["Granulomatosis de células de Langerhans unifocal","Histiocitosis X unifocal"]},"it":{"name":"Unifocal Langerhans cell histiocytosis"},"nl":{"name":"Unifocale langerhanscelhistiocytose","synonyms":["Unifocale histiocytose X","Unifocale langerhanscelgranulomatose"]},"pt":{"name":"Histiocitose unifocal de células Langerhans","synonyms":["Granulomatose unifocal de células Langerhans","Histiocitose X unifocal"]},"pl":{"name":"Jednoogniskowa histiocytoza z komórek Langerhansa","synonyms":["Unifocal Langerhans cell granulomatosis","Unifocal histiocytosis X"]},"cs":{"name":"Unifokální histiocytóza z Langerhansových buněk","synonyms":["Unifocal Langerhans cell granulomatosis","Unifocal histiocytosis X"]}},"xrefs":[],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98023,"name":"Rare systemic or rheumatologic disease"},"parents":[{"orpha":389,"name":"Langerhans cell histiocytosis","classifications":[184,194,196,202,233]}],"children":[],"genes":[{"symbol":"BRAF","name":"B-Raf proto-oncogene, serine/threonine kinase","gene_type":"gene with protein product","association":"Disease-causing somatic mutation(s) in","status":"Assessed","source":"22996177[PMID]","hgnc":"1097","ensembl":"ENSG00000157764","omim":"164757","loci":["7q34"]}],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":[],"prevalence":[],"phenotypes":null}