{"orpha":675404,"name":"May-Thurner syndrome","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Cockett syndrome","MTS"],"definition":"A rare vascular disease characterized by venous insufficiency, obstruction or thrombosis usually caused by compression of the left common iliac vein between the right common iliac artery and the underlying spine with subsequent development of a left deep vein thrombosis (DVT). Patients may present with pain, swelling, venous stasis ulcers, skin pigmentation changes and post-thrombotic syndrome.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-675404/","orphanet_url":"https://www.orpha.net/en/disease/detail/675404","names":{"fr":{"name":"Syndrome de May-Thurner","synonyms":["Syndrome de Cockett"],"definition":"Maladie vasculaire rare caractérisée par une insuffisance, une obstruction ou une thrombose veineuse, généralement causée par une compression de la veine iliaque commune gauche par l'artère iliaque droite contre les vertèbres lombaires, entraînant le développement d'une thrombose veineuse profonde (TVP) gauche. Les patients peuvent présenter des douleurs, un gonflement, des ulcères de stase veineuse, des modifications de la pigmentation cutanée et un syndrome post-thrombotique."},"de":{"name":"May-Thurner-Syndrom","synonyms":["Cockett-Syndrom","MTS"]},"es":{"name":"Síndrome de May-Thurner","synonyms":["Síndrome de Cockett"]},"it":{"name":"Sindrome di May-Thurner","synonyms":["SMT","Sindrome di Cockett"]},"nl":{"name":"Syndroom van May-Thurner","synonyms":["MTS","Syndroom van Cockett"],"definition":"Een zeldzame vasculaire ziekte, gekenmerkt door veneuze insufficiëntie, obstructie of trombose meestal veroorzaakt door compressie van linker vena iliaca communis (gemeenschappelijke heupader) tussen de rechter arteria iliaca communis (gemeenschappelijke heupslagader) en de onderliggende wervelkolom met ontwikkeling van een linker diepveneuze trombose (DVT). Patiënten kunnen zich presenteren met pijn, zwelling, ulcus cruris venosum (open been), veranderingen van huidpigmentatie, en posttrombotisch syndroom."},"pt":{"name":"Síndrome May-Thurner","synonyms":["MTS","Síndrome Cockett"]},"pl":{"name":"Zespół May-Thurnera","synonyms":["Cockett syndrome","MTS"]},"cs":{"name":"May-Thurnerův syndrom","synonyms":["Mayův-Thurnerův syndrom"]},"uk":{"name":"Синдром Мей-Тернера","synonyms":["Синдром Кокета","МТС"]}},"xrefs":[{"source":"ICD-10","code":"I87.1","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"BD73.2Y","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0043361","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"43361","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C3165062","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10069727","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98028,"name":"Rare circulatory system disease"},"parents":[{"orpha":496924,"name":"Non-inflammatory vasculopathy","classifications":[198]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":[],"prevalence":[],"phenotypes":null}