{"orpha":664912,"name":"Neonatal renal venous thrombosis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["NRVT","Neonatal RVT"],"definition":"A rare vascular condition characterized by the formation of a thrombus (blood clot) in the renal vein of a newborn infant, typically within the first 28 days of life. This condition can cause renal (kidney) ischemia, and may lead to kidney damage, swelling, and potential loss of kidney function. Neonatal renal vein thrombosis (NRVT) can affect one kidney (unilateral) or both kidneys (bilateral), with the severity of symptoms often depending on the extent of the clot and the number of affected kidneys.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-664912/","orphanet_url":"https://www.orpha.net/en/disease/detail/664912","names":{"fr":{"name":"Thrombose néonatale des veines rénales","synonyms":["TNVR","Thrombose veineuse rénale néonatale"],"definition":"Maladie vasculaire rare caractérisée par la formation d'un thrombus (caillot sanguin) dans la veine rénale d'un nouveau-né, généralement au cours des 28 premiers jours de vie. La maladie peut provoquer une ischémie rénale et causer des lésions rénales, un gonflement et une éventuelle perte de la fonction rénale. La thrombose néonatale des veines rénales (TNVR) peut toucher un seul rein (thrombose unilatérale) ou les deux reins (thrombose bilatérale), et la gravité des symptômes dépend souvent de la taille du caillot sanguin et du nombre de reins touchés."},"de":{"name":"Nierenvenenthrombose, neonatale","synonyms":["NRVT"]},"es":{"name":"Trombosis venosa renal neonatal","synonyms":["TVR neonatal"]},"it":{"name":"Trombosi venosa renale neonatale","synonyms":["TVR neonatale","TVRN"]},"nl":{"name":"Neonatale trombose van vena renalis","synonyms":["NRVT","Neonatale RVT","Neonatale renale veneuze trombose"],"definition":"Een zeldzame vasculaire aandoening, gekenmerkt door vorming van een trombus (bloedstolsel) in een nierader (vena renalis) van een neonaat, doorgaans binnen de eerste 28 dagen na de geboorte. Deze aandoening kan ischemie van nier veroorzaken, en kan leiden tot nierschade, zwelling van de nier, en mogelijk verlies van nierfunctie. Neonatale trombose van vena renalis (NRVT) kan één nier (unilateraal) of beide nieren (bilateraal) treffen, en de ernst van de symptomen hangt vaak af van de omvang van het bloedstolsel en het aantal aangetaste nieren."},"pt":{"name":"Trombose venosa renal neonatal","synonyms":["NRVT","RVT neonatal"]},"pl":{"name":"Zakrzepica żył nerkowych noworodków","synonyms":["NRVT","Neonatal RVT"]},"cs":{"name":"Novorozenecká trombóza renální žíly","synonyms":["NRVT","Neonatal RVT"]},"uk":{"name":"Неонатальний тромбоз ниркових вен","synonyms":["Неонатальна RVT","NRVT"]}},"xrefs":[{"source":"ICD-10","code":"P29.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"GB90.3","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0971105","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"971105","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5925061","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93626,"name":"Rare renal disease"},"parents":[{"orpha":93626,"name":"Rare renal disease","classifications":[188]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Unknown"],"onset":["Antenatal","Neonatal"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.13,"area":"Canada","status":"Validated","source":"35372933[PMID]_ORPHANET"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.11,"area":"Germany","status":"Validated","source":"10653328[PMID]_ORPHANET"}],"phenotypes":null}