{"orpha":664450,"name":"Inherited cancer-predisposing lymphoproliferative syndrome","type":"Category","group":"Group of disorders","status":"active","flags":[],"synonyms":[],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-664450/","orphanet_url":"https://www.orpha.net/en/disease/detail/664450","names":{"fr":{"name":"Syndrome lymphoprolifératif héréditaire prédisposant aux cancers"},"de":{"name":"Hereditäres Lymphoproliferatives Syndrom mit Krebsprädisposition"},"es":{"name":"Síndrome linfoproliferativo hereditario con predisposición al cáncer"},"it":{"name":"Sindrome ereditaria linfoproliferativa predisponente ai tumori"},"nl":{"name":"Erfelijk lymfoproliferatief syndroom met tumorpredispositie"},"pt":{"name":"Síndrome de cancro hereditário-predisposição linfoproliferativa"},"pl":{"name":"Dziedziczny zespół limfoproliferacyjny predysponujący do nowotworów"},"cs":{"name":"Dědičný lymfoproliferativní syndrom predisponující k nádorovým onemocněním"},"uk":{"name":"Спадковий лімфопроліферативний синдром, що призводить до раку"}},"xrefs":[{"source":"UMLS","code":"C5925057","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[{"type":"Referred to","orpha":238510,"name":"OBSOLETE: Lymphoproliferative syndrome","status":"inactive"}],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":140162,"name":"Inherited cancer-predisposing syndrome","classifications":[156,202]}],"children":[{"orpha":3261,"name":"Autoimmune lymphoproliferative syndrome","type":"Disease"},{"orpha":436159,"name":"Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsuffiency","type":"Disease"},{"orpha":3453,"name":"Autoimmune polyendocrinopathy type 1","type":"Disease"},{"orpha":238505,"name":"Combined immunodeficiency due to CD27 deficiency","type":"Disease"},{"orpha":697389,"name":"Combined immunodeficiency due to HELIOS deficiency","type":"Disease"},{"orpha":538963,"name":"Combined immunodeficiency due to ITK deficiency","type":"Disease"},{"orpha":695172,"name":"Combined immunodeficiency due to dimerization defective IKAROS mutation","type":"Disease"},{"orpha":275523,"name":"Dianzani autoimmune lymphoproliferative disease","type":"Disease"},{"orpha":542301,"name":"EBV-induced lymphoproliferative disease due to CARMIL2 deficiency","type":"Disease"},{"orpha":664726,"name":"EBV-induced lymphoproliferative disease due to CD137 deficiency","type":"Disease"},{"orpha":538958,"name":"EBV-induced lymphoproliferative disease due to CD70 deficiency","type":"Disease"},{"orpha":420573,"name":"EBV-induced lymphoproliferative disease due to CTPS1 deficiency","type":"Disease"},{"orpha":664711,"name":"EBV-induced lymphoproliferative disease due to PRKCD deficiency","type":"Disease"},{"orpha":664699,"name":"EBV-induced lymphoproliferative disease due to RASGRP1 deficiency","type":"Disease"},{"orpha":664729,"name":"EBV-induced lymphoproliferative disease due to TET2 deficiency","type":"Disease"},{"orpha":619948,"name":"Early-onset autoimmunity-autoinflammation-immunodeficiency syndrome due to SOCS1 haploinsufficiency","type":"Disease"},{"orpha":306550,"name":"FADD-related immunodeficiency","type":"Disease"},{"orpha":540,"name":"Familial hemophagocytic lymphohistiocytosis","type":"Disease"},{"orpha":695807,"name":"Immunodeficiency-systemic inflammation-lymphoma predisposition syndrome","type":"Disease"},{"orpha":696874,"name":"NFKB1-related immune dysregulation","type":"Disease"},{"orpha":268114,"name":"RAS-associated autoimmune leukoproliferative disease","type":"Disease"},{"orpha":391487,"name":"STAT1-related autoimmune enteropathy and endocrinopathy-susceptibility to chronic infections syndrome","type":"Disease"},{"orpha":438159,"name":"STAT3-related early-onset multisystem autoimmune disease","type":"Disease"},{"orpha":538931,"name":"X-linked lymphoproliferative disease due to SAP deficiency","type":"Disease"},{"orpha":317476,"name":"XMEN","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}