{"orpha":658,"name":"Non-histaminic angioedema","type":"Clinical group","group":"Group of disorders","status":"active","flags":[],"synonyms":["Angioneurotic edema","Bradykinine-induced angioedema","Non histamine-induced angioedema"],"definition":"A disorder that is characterized by the occurrence of transitory and recurrent subcutaneous and/or submucosal edemas resulting in swelling and/or abdominal pain.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-658/","orphanet_url":"https://www.orpha.net/en/disease/detail/658","names":{"fr":{"name":"Angio-oedème","synonyms":["Angio-oedème bradykinique","Angio-oedème non histaminique","OAN","Oedème angioneurotique"],"definition":"L'angioedème se caractérise par la survenue d'oedèmes sous-cutanés et/ou sous-muqueux transitoires et récidivants responsables d'un gonflement localisé et/ou de douleur abdominale."},"de":{"name":"Angioödem, nicht-Histamin-vermitteltes","synonyms":["Angioödem, Bradykinin-induziertes","Nicht-Histamin-induziertes Angioödem","Ödem, angioneurotisches"],"definition":"Das Angioödem ist gekennzeichnet durch vorübergehende und rezidivierende subkutane und/oder submuköse Ödeme mit Schwellungen und Leibschmerzen."},"es":{"name":"Angioedema no histamínico","synonyms":["Angioedema inducido por bradiquinina","Angioedema no inducido por histamina","Edema angioneurótico"],"definition":"Es una enfermedad caracterizada por la aparición recurrente y transitoria de edemas subcutáneos y/o de la submucosa, que provocan inflamación y dolor abdominal."},"it":{"name":"Angioedema non istaminico","synonyms":["Angioedema indotto dalla bradichinina","Angioedema non indotto dall'istamina","Edema angioneurotico"],"definition":"L'angioedema è caratterizzato dalla comparsa di edemi sottomucosi e/o sottocutanei ricorrenti e transitori, che causano dolori addominali e gonfiori."},"nl":{"name":"Niet-histamine-geïnduceerd angio-oedeem","synonyms":["Angioneurotisch oedeem","Bradykinine-geïnduceerd angio-oedeem"],"definition":"Een aandoening, gekarakteriseerd door tijdelijke en terugkerende subcutane en/of submucosale oedemen die resulteren in zwelling en/of abdominale pijn."},"pt":{"name":"Angioedema não-histamínico","synonyms":["Angioedema"],"definition":"Doença caracterizada pela ocorrência de edemas subcutâneos e/ou submucosos transitórios e recorrentes, resultando em inchaço e/ou dor abdominal."},"pl":{"name":"Obrzęk naczynioruchowy niehistaminowy","synonyms":["Obrzęk naczynioruchowy","Obrzęk naczynioruchowy indukowany bradykininą","Obrzęk naczynioruchowy nieindukowany histaminą"]},"cs":{"name":"Non-histaminový angioedém","synonyms":["Angioneurotický edém","Bradykininem-indukovaný angioedém","Non-histaminem indukovaný angioedém"]},"uk":{"name":"Негістамінний ангіоневротичний набряк","synonyms":["Ангіоневротичний набряк","Ангіоневротичний набряк, спричинений брадикініном","Ангіоневротичний набряк, не викликаний гістаміном"],"definition":"A disorder that is characterized by the occurrence of transitory and recurrent subcutaneous and/or submucosal edemas resulting in swelling and/or abdominal pain."},"zh":{"name":"非组胺源性血管性水肿","synonyms":["非组胺源性血管性水肿"]},"tr":{"name":"Histaminik olmayan anjiyoödem","synonyms":["Anjiyonörotik ödem","Bradikininin neden olduğu anjiyoödem","Histamin kaynaklı olmayan anjiyoödem"]}},"xrefs":[{"source":"MONDO","code":"0019013","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"19013","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0002994","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98004,"name":"Rare immune disease"},"parents":[{"orpha":98004,"name":"Rare immune disease","classifications":[195]}],"children":[{"orpha":91385,"name":"Acquired angioedema","type":"Clinical group"},{"orpha":91378,"name":"Hereditary angioedema","type":"Clinical group"}],"genes":[],"genes_via_subtypes":[],"inheritance":["Autosomal dominant","Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"1-9 / 100 000","value":0.0,"area":"Europe","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}