{"orpha":64722,"name":"Granulomatous mastitis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["IGM","Idiopathic granulomatous mastitis"],"definition":"A rare gynecologic or obstetric disease characterized by a painful, palpable breast mass with relative sparing of the subareolar regions, often associated with inflammation of the overlying skin and accompanied by axillary lymphadenopathy. It usually occurs in young parous women with a history of breast-feeding. The diagnosis of idiopathic granulomatous mastitis requires that other granulomatous lesions in the breast be excluded.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-64722/","orphanet_url":"https://www.orpha.net/en/disease/detail/64722","names":{"fr":{"name":"Mastite granulomateuse","synonyms":["GMI","Mastite granulomateuse idiopathique"],"definition":"Maladie gynécologique ou obstétrique rare autre que malformative caractérisée par une masse mammaire douloureuse et discernable à la palpation, épargnant les régions sous-aréolaires, souvent associée à une inflammation du revêtement cutané et accompagnée d'une lymphadénopathie axillaire. Elle survient généralement chez les jeunes femmes en période d'activité génitale ayant des antécédents d'allaitement. Le diagnostic de mastite granulomateuse idiopathique nécessite l'exclusion d'autres lésions granulomateuses du sein."},"de":{"name":"Granulomatöse Mastitis","synonyms":["Granulomatöse Mastitis, idiopathische","IGM"],"definition":"Eine seltene gynäkologische oder geburtshilfliche Erkrankung, die durch eine schmerzhafte, tastbare Gewebeverdichtung in der Brust gekennzeichnet ist, bei der die subareolären Regionen relativ wenig betroffen sind und die häufig mit einer Entzündung der darüber liegenden Haut und einer axillären Lymphadenopathie einhergeht. Sie tritt in der Regel bei jungen parous Frauen auf, die in der Vergangenheit gestillt haben. Die Diagnose einer idiopathischen granulomatösen Mastitis erfordert den Ausschluss anderer granulomatöser Läsionen in der Brust."},"es":{"name":"Mastitis granulomatosa","synonyms":["Mastitis granulomatosa idiopática"],"definition":"Es una enfermedad ginecológica u obstétrica poco frecuente caracterizada por una masa mamaria palpable y dolorosa con una relativa conservación de la región subareolar, que a menudo asocia inflamación de la piel suprayacente y va acompañada de linfadenopatía axilar. Por lo general, ocurre en mujeres que han sido madres jóvenes con antecedentes de lactancia. El diagnóstico de la mastitis granulomatosa idiopática requiere de la exclusión de otras lesiones granulomatosas mamarias."},"it":{"name":"Mastite granulomatosa","synonyms":["IGM","Mastite granulomatosa idiopatica"],"definition":"Si tratta di una malattia ostetrico-ginecologica rara, caratterizzata da una massa mammaria palpabile dolorosa; le regioni alveolari sono relativamente risparmiate. Spesso si associa all'infiammazione della cute sovrastante e ad una linfoadenopatia ascellare. In genere colpisce le giovani donne che hanno avuto figli e hanno allattano al seno. La diagnosi si basa sull'esclusione di altre lesioni mammarie granulomatose."},"nl":{"name":"Granulomateuze mastitis","synonyms":["Idiopathische granulomateuze mastitis","IGM"],"definition":"Een zeldzame gynaecologische of obstetrische ziekte, gekarakteriseerd door een pijnlijke, tastbare massa in borst waarbij de subareolaire regio's relatief gespaard blijven, vaak geassocieerd met inflammatie van bovenliggende huid en vergezeld van axillaire lymfadenopathie. De aandoening komt meestal voor bij jonge vrouwen die reeds een kind hebben gebaard en een geschiedenis van borstvoeding hebben. Diagnose van idiopathische granulomateuze mastitis vereist dat andere granulomateuze laesies van borst worden uitgesloten."},"pt":{"name":"Mastite granulomatosa","synonyms":["Mastite granulomatosa idiopática"]},"pl":{"name":"Ziarniniakowe zapalenie sutka","synonyms":["Idiopatyczne ziarniniakowe zapalenie sutka"]},"cs":{"name":"Granulomatózní mastitida","synonyms":["Idiopatická granulomatózní mastitida"]},"uk":{"name":"Гранулематозний мастит","synonyms":["Ідіопатичний гранулематозний мастит"],"definition":"A rare gynecologic or obstetric disease characterized by a painful, palpable breast mass with relative sparing of the subareolar regions, often associated with inflammation of the overlying skin and accompanied by axillary lymphadenopathy. It usually occurs in young parous women with a history of breast-feeding. The diagnosis of idiopathic granulomatous mastitis requires that other granulomatous lesions in the breast be excluded."},"zh":{"name":"肉芽肿性乳腺炎","synonyms":["特发性肉芽肿性乳腺炎"]},"tr":{"name":"Granülomatöz mastit","synonyms":["İdiyopatik granülomatöz mastit"]}},"xrefs":[{"source":"ICD-10","code":"N61","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"GB21.Y","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0018987","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D058890","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0405469","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":96344,"name":"Rare gynecologic or obstetric disease"},"parents":[{"orpha":180202,"name":"Rare non-malformative breast disease","classifications":[205]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["Adolescent","Adult","Elderly"],"prevalence":[{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 100 000","value":2.4,"area":"Worldwide","status":"Validated","source":"38304866[PMID]"}],"phenotypes":null}