{"orpha":64694,"name":"Trench fever","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Bartonellosis due to Bartonella quintana infection"],"definition":"A rare bacterial infectious disease caused by the louse-borne bacterium <i>Bartonella quintana</i> and characterized by a variable clinical picture with acute or insidious onset of a (potentially relapsing) febrile illness, headache, leg pain (most typically the shinbone), endocarditis, and thrombocytopenia. There may also be only non-specific symptoms that mimic other infections. The disease nowadays most commonly affects socially disadvantaged persons in urban areas.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-64694/","orphanet_url":"https://www.orpha.net/en/disease/detail/64694","names":{"fr":{"name":"Fièvre des tranchées","synonyms":["Bartonellose à Bartonella quintana"],"definition":"Maladie infectieuse bactérienne rare causée par la bactérie <i>Bartonella quintana</i> transmise par les poux et caractérisée par un tableau clinique variable avec apparition aiguë ou insidieuse d'une maladie fébrile (potentiellement récidivante), des maux de tête, des douleurs dans les jambes (le plus souvent le tibia), d'une endocardite et d'une thrombocytopénie. Les symptômes peuvent également être non spécifiques, semblables à ceux d'autres infections. La maladie touche le plus souvent des personnes socialement défavorisées dans les zones urbaines."},"de":{"name":"Schützengrabenfieber","synonyms":["Bartonellose durch Infektion mit Bartonella quintana","Wolhynisches Fieber"],"definition":"Eine seltene bakterielle Infektionskrankheit, die durch das von Läusen übertragene Bakterium <i>Bartonella quintana</i> verursacht wird und durch ein variables klinisches Bild mit akutem oder schleichendem Beginn einer (möglicherweise rezidivierenden) fiebrigen Erkrankung, Kopf- und Beinschmerzen (am häufigsten am Schienbein), Endokarditis und Thrombozytopenie gekennzeichnet ist. Es können auch nur unspezifische Symptome auftreten, die andere Infektionen imitieren. Die Krankheit betrifft heute vor allem sozial benachteiligte Personen in städtischen Gebieten."},"es":{"name":"Fiebre de las trincheras","synonyms":["Bartonelosis por una infección por Bartonella quintana"],"definition":"Es una enfermedad infecciosa bacteriana poco frecuente causada por la bacteria <i>Bartonella quintana</i> transmitida por piojos y caracterizada por un cuadro clínico variable con un inicio agudo o insidioso de enfermedad febril (potencialmente recurrente), cefalea, dolor en las piernas (más típicamente en las tibias), endocarditis y trombocitopenia. También puede presentar únicamente síntomas inespecíficos, semejantes a otras infecciones. En la actualidad, la enfermedad afecta con mayor frecuencia a personas socialmente desfavorecidas de las zonas urbanas."},"it":{"name":"Febbre delle trincee","synonyms":["Bartonellosi dovuta a infezione da Bartonella quintana"],"definition":"Si tratta di una malattia infettiva batterica rara, causata dal batterio <i>Bartonella quintana</i> trasmesso dai pidocchi. Il quadro clinico è variabile, ha un esordio acuto o insidioso, e comprende una malattia febbrile (potenzialmente recidivante), la cefalea, il dolore alle gambe (in genere alle tibie), l'endocardite e la trombocitopenia. I pazienti possono anche presentare solo sintomi aspecifici che ricordano quelli di altre infezioni. Oggi la malattia colpisce per lo più le persone socialmente svantaggiate che vivono nelle aree urbane."},"nl":{"name":"Loopgravenkoorts","synonyms":["Bartonellose door infectie door Bartonella quintana"],"definition":"Een zeldzame, bacteriële infectieziekte, veroorzaakt door de door luizen overgedragen bacterie <i>Bartonella quintana</i>, en gekarakteriseerd door een variabel klinisch beeld met acute of sluipende aanvang van (potentieel recidiverende) febriele ziekte, hoofdpijn, pijn in been (meestal scheenbeen), endocarditis, en trombocytopenie. Het is ook mogelijk dat enkel niet-specifieke symptomen aanwezig zijn, die andere infecties nabootsen. Vandaag treft de ziekte vooral sociaal benadeelde personen in stedelijke gebieden."},"pt":{"name":"Febre das trincheiras","synonyms":["Bartonelose devido a infeção por Bartonella quintana"]},"pl":{"name":"Gorączka okopowa","synonyms":["Bartonelloza spowodowana infekcją Bartonella quintana"]},"cs":{"name":"Zákopová horečka","synonyms":["Bartonelóza způsobená infekcí Bartonella quintana"]},"uk":{"name":"Окопна лихоманка","synonyms":["Бартонельоз, спричинений інфекцією Bartonella quintana"],"definition":"A rare bacterial infectious disease caused by the louse-borne bacterium <i>Bartonella quintana</i> and characterized by a variable clinical picture with acute or insidious onset of a (potentially relapsing) febrile illness, headache, leg pain (most typically the shinbone), endocarditis, and thrombocytopenia. There may also be only non-specific symptoms that mimic other infections. The disease nowadays most commonly affects socially disadvantaged persons in urban areas."},"zh":{"name":"战壕热","synonyms":["五日热巴尔通体感染所致巴尔通体病"]},"tr":{"name":"Siper humması","synonyms":["Bartonella quintana enfeksiyonuna bağlı bartonelloz"]}},"xrefs":[{"source":"ICD-10","code":"A79.0","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"1C11.1","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1587737629"},{"source":"MONDO","code":"0005991","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D014205","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0040830","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10044582","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":163582,"name":"Rare bacterial infectious disease","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":null}