{"orpha":620198,"name":"Non-syndromic bicoronal and metopic craniosynostosis","type":"Morphological anomaly","group":"Disorder","status":"active","flags":[],"synonyms":["Isolated bicoronal and metopic craniosynostosis","Non-syndromic bilateral coronal and metopic suture synostosis"],"definition":"A form of non-syndromic multisutural craniosynostosis characterized by premature fusion of the bicoronal and metopic sutures, resulting in brachycephaly and trigonocephaly.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-620198/","orphanet_url":"https://www.orpha.net/en/disease/detail/620198","names":{"fr":{"name":"Craniosynostose bicoronale et métopique non syndromique","synonyms":["Craniosynostose bicoronale et métopique isolée","Craniosynostose coronale bilatérale et sagittale non syndromique"],"definition":"Forme de craniosynostose multisuturaire non syndromique caractérisée par une fusion prématurée des sutures bicoronale et métopique, entraînant une brachycéphalie et une trigonocéphalie."},"de":{"name":"Kraniosynostose, bikoronale und metopische, nicht-syndromale","synonyms":["Bilaterale Synostose der koronalen und metopischen Naht, nicht-syndromale","Isolierte bikoronale und metopische Kraniosynostose"],"definition":"Eine Form der nicht-syndromalen multisuturalen Kraniosynostose, die durch eine vorzeitige Verschmelzung der bikoronalen und metopischen Nähte gekennzeichnet ist und zu Brachyzephalie und Trigonozephalie führt."},"es":{"name":"Craneosinostosis bicoronal y metópica no sindrómica","synonyms":["Craneosinostosis bicoronal y metópica aislada","Sinostosis de sutura coronal y metópica bilateral no sindrómica"],"definition":"Es una forma de craneosinostosis multisutural no sindrómica caracterizada por la fusión prematura de las suturas bicoronal y metópica, lo que produce braquicefalia y trigonocefalia."},"it":{"name":"Craniosinostosi bicoronale e metopica non sindromica","synonyms":["Craniosinostosi isolata bicoronale e metopica","Sinostosi della sutura metopica e coronale bilaterale non sindromica"]},"nl":{"name":"Niet-syndromale bicoronale en metopische craniosynostose","synonyms":["Geïsoleerde bicoronale en metopische craniosynostose","Niet-syndromale metopische en bilaterale coronale synostose","Niet-syndromale synostose van bilaterale kroonnaad en voorhoofdsnaad","Niet-syndromale synostose van bilaterale sutura coronalis en sutura metopica"],"definition":"Een vorm van niet-syndromale multisuturale craniosynostose, gekenmerkt door premature fusie van de beide kroonnaden (sutura coronalis) en de voorhoofdsnaden (sutura metopica), wat resulteert in brachycefalie en trigonocefalie."},"pt":{"name":"Craniossinostose metópica e bicoronal não-sindromática","synonyms":["Craniossinostose metópica e bicoronal isolada","Sinostose da sutura metópica e coronal bilateral não-sindromática"]},"pl":{"name":"Niesyndromiczna kraniosynostoza obejmująca oba szwy wieńcowe oraz szew czołowy","synonyms":["Isolated bicoronal and metopic craniosynostosis","Non-syndromic bilateral coronal and metopic suture synostosis"],"definition":"Postać niesyndromicznej kraniosynostozy, charakteryzująca się przedwczesnym zrośnięciem szwów wieńcowych i metopicznych, co powoduje brachycefalię i trigonocefalię."},"cs":{"name":"Nesyndromická bikoronární a metopická kraniosynostóza","synonyms":["Isolated bicoronal and metopic craniosynostosis","Non-syndromic bilateral coronal and metopic suture synostosis"]},"uk":{"name":"Несиндромальний бікоронарний та метопічний краніосиностоз","synonyms":["Ізольований бікорональний та метопічний краніосиностоз","Несиндромний двосторонній синостоз коронарного та метопічного швів"]}},"xrefs":[{"source":"ICD-10","code":"Q75.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"LB70.0Y","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0850082","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5680394","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":620152,"name":"Non-syndromic multisutural craniosynostosis","classifications":[147,156,199]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Autosomal recessive"],"onset":["Neonatal"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"<1 / 1 000 000","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":null}