{"orpha":617440,"name":"Painful legs and moving toes syndrome","type":"Clinical syndrome","group":"Disorder","status":"active","flags":[],"synonyms":["PLMT syndrome"],"definition":"A rare neurologic (adult-onset) movement disorder characterized by persistent pain (unilateral or bilateral) in the feet or legs (most commonly the hemi-lower limbs) and persistant twisting, non-rhythmic, involuntary movements of one or more toes. Chronic \"deep aching pulling pain\" includes tingling, numbness, aching, dullness, cramp, shooting, sharp, burning, and prickling.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-617440/","orphanet_url":"https://www.orpha.net/en/disease/detail/617440","names":{"fr":{"name":"Syndrome de jambes douloureuses et orteils instables","definition":"Anomalie neurologique rare du mouvement, apparaissant à l'âge adulte, caractérisée par une douleur persistante (unilatérale ou bilatérale) dans les pieds ou les jambes (le plus souvent de la moitié inférieure des membres inférieurs) et des mouvements persistants de torsion, non rythmiques et involontaires d'un ou de plusieurs orteils. Les «&nbsp;douleurs profondes et lancinantes&nbsp;» chroniques comprennent les fourmillements, les engourdissements, les courbatures, les tiraillements, les crampes, les douleurs aiguës, les brûlures et les picotements."},"de":{"name":"Syndrom der schmerzenden Beine und beweglichen Zehen","synonyms":["PLMT-Syndrom"],"definition":"Eine seltene neurologische Bewegungsstörung des Erwachsenen, die durch anhaltende Schmerzen (einseitig oder beidseitig) in den Füßen oder Beinen (am häufigsten in den unteren Gliedmaßen) und anhaltende, unrhythmische, unwillkürliche Drehbewegungen einer oder mehrerer Zehen gekennzeichnet ist. Chronische ,,tiefe, ziehende Schmerzen'' umfassen Kribbeln, Taubheitsgefühl, Schmerzen, Taubheit, Krämpfe, stechende, brennende und prickelnde Schmerzen."},"es":{"name":"Síndrome de piernas dolorosas y dedos de los pies en movimiento","synonyms":["Síndrome PLMT"],"definition":"Es un trastorno neurológico del movimiento poco frecuente (que debuta en la edad adulta) caracterizado por dolor persistente (uni- o bilateral) en los pies o las piernas (más comúnmente en las extremidades inferiores) y movimientos persistentes, arrítmicos e involuntarios de torsión de uno o más dedos de los pies. El \"dolor profundo\" de carácter crónico incluye hormigueo, entumecimiento, embotamiento, calambres, punzadas, ardor y picazón."},"it":{"name":"Sindrome delle gambe dolorose e del movimento delle dita dei piedi","synonyms":["Sindrome PLMT"]},"nl":{"name":"Syndroom van pijnlijke benen en bewegende tenen","synonyms":["PLMT-syndroom"],"definition":"Een zeldzame neurologische (volwassen aanvang) bewegingsstoornis, gekenmerkt door aanhoudende pijn (unilateraal of bilateraal) in voet of been (doorgaans eenzijdig aan onderste ledemaat) en persisterende draaiende, niet-ritmische, onvrijwillige bewegingen van een of meer tenen. Chronische diepliggende trekkende pijn wordt gekarakteriseerd als tintelingen, gevoelloosheid, pijnlijk gevoel, doof gevoel, krampen, pijnscheuten, scherpe pijn, brandend gevoel, en prikkelend gevoel."},"pt":{"name":"Síndrome das pernas doridas e dedos móveis","synonyms":["Síndrome PLMT"],"definition":"Doença neurológica do movimento rara (de início na idade adulta) caracterizada por dor persistente (unilateral ou bilateral) nos pés ou pernas (mais comummente nos membros hemi-inferiores) e movimentos persistentes de torção, não rítmicos e involuntários de um ou mais dedos. A dor crónica profunda e intensa inclui formigueiro, dormência, dor, embotamento, cãibra, pontadas, ardor e picadas."},"pl":{"name":"Zespół bolesnych nóg i niespokojnych palców","synonyms":["PLMT syndrome"],"definition":"Rzadkie neurologiczne zaburzenie ruchowe (o początku w wieku dorosłym), charakteryzujące się utrzymującym się bólem (jednostronnym lub obustronnym) stóp lub nóg (najczęściej dolnej połowy kończyn dolnych) oraz ciągłymi skrętnymi, nierytmicznymi, mimowolnymi ruchami jednego lub większej liczby palców u nóg. Przewlekły „głęboki rwąco-ciągnący ból” opisywany jest jako mrowienie, drętwienie, uczucie rwania, ból tępy, skurcze, strzelanie, ból ostry, pieczenie i kłucie."},"cs":{"name":"Syndrom bolestivých nohou a pohyblivých prstů na nohou","synonyms":["PLMT syndrome"]},"uk":{"name":"Синдром болю в ногах і рухомих пальців ніг","synonyms":["Синдром PLMT"],"definition":"A rare neurologic (adult-onset) movement disorder characterized by persistent pain (unilateral or bilateral) in the feet or legs (most commonly the hemi-lower limbs) and persistant twisting, non-rhythmic, involuntary movements of one or more toes. Chronic \"deep aching pulling pain\" includes tingling, numbness, aching, dullness, cramp, shooting, sharp, burning, and prickling."}},"xrefs":[{"source":"ICD-10","code":"G25.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0850049","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5680388","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"12706","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10089938","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":102003,"name":"Rare movement disorder","classifications":[181]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adult"],"prevalence":[{"type":"Cases/families","qualification":"Case(s)","class":null,"value":144.0,"area":"Worldwide","status":"Validated","source":"39585061[PMID]"},{"type":"Point prevalence","qualification":"Class only","class":"<1 / 1 000 000","value":0.0,"area":"Worldwide","status":"Validated","source":"39585061[PMID]_ORPHANET"}],"phenotypes":null}