{"orpha":60026,"name":"Pulmonary nodular lymphoid hyperplasia","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Pulmonary pseudolymphoma"],"definition":"Pulmonary nodular lymphoid hyperplasia (PNHL) is a reactive lymphoid proliferation manifesting as solitary or multiple nodules in the lung.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-60026/","orphanet_url":"https://www.orpha.net/en/disease/detail/60026","names":{"fr":{"name":"Hyperplasie lymphoïde nodulaire pulmonaire","synonyms":["Pseudolymphome du poumon"],"definition":"Prolifération lymphoïde réactive se manifestant par des nodules solitaires ou multiples situés dans les poumons."},"de":{"name":"Hyperplasie, lymphoide pulmonale noduläre","synonyms":["Pseudolymphom, pulmonales"]},"es":{"name":"Hiperplasia linfoide nodular y pulmonar","synonyms":["Pseudolinfoma pulmonar"],"definition":"Es una proliferación linfoide reactiva que se manifiesta como nódulos solitarios o múltiples en el pulmón."},"it":{"name":"Iperplasia linfatica nodulare polmonare","synonyms":["Pseudolinfoma polmonare"]},"nl":{"name":"Pulmonale nodulaire lymfoïdhyperplasie","synonyms":["Pulmonaal pseudolymfoom"],"definition":"Pulmonale nodulaire lymfoïdhyperplasie (PNHL) is een reactieve lymfoïdproliferatie die zich manifesteert als alleenstaande of meerdere knobbels in de long."},"pt":{"name":"Hiperplasia linfóide nodular pulmonar","synonyms":["Pseudo-linfoma pulmonar"]},"pl":{"name":"Guzkowy rozrost limfoidalny płuc","synonyms":["Pseudochłoniak płuc"]},"cs":{"name":"Plicní nodulární lymfoidní hyperplázie","synonyms":["Plicní pseudolymfom"]},"uk":{"name":"Вузлова лімфоїдна гіперплазія легень","synonyms":["Псевдолімфома легень"],"definition":"Pulmonary nodular lymphoid hyperplasia (PNHL) is a reactive lymphoid proliferation manifesting as solitary or multiple nodules in the lung."},"zh":{"name":"肺假性淋巴瘤","synonyms":["肺假性淋巴瘤"]},"tr":{"name":"Pulmoner nodüler lenfoid hiperplazi","synonyms":["Pulmoner psödolenfoma"]}},"xrefs":[{"source":"OMIM","code":"178610","qualifier":"E","icd_relation":null,"validated":true},{"source":"ICD-10","code":"J98.4","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"CB40.Y","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0008348","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C1334969","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10077412","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97955,"name":"Rare respiratory disease"},"parents":[{"orpha":101944,"name":"Rare pulmonary disease","classifications":[184]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["Adolescent","Adult","Childhood"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2021-01-20","source":"29902913[PMID]_30720334[PMID]_28609772[PMID]","terms":[{"hpo":"HP:0012735","label":"Cough","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002729","label":"Follicular hyperplasia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0100721","label":"Mediastinal lymphadenopathy","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0025392","label":"Nodular pattern on pulmonary HRCT","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0030150","label":"Plasmacytosis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0100749","label":"Chest pain","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002094","label":"Dyspnea","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0025179","label":"Ground-glass opacification on pulmonary HRCT","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0030057","label":"Autoimmune antibody positivity","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0002721","label":"Immunodeficiency","frequency":"Very rare (<4-1%)","criteria":null}]}}