{"orpha":599507,"name":"Acquired factor XI deficiency","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["aFXI"],"definition":null,"note":null,"url":"https://raremap.alftech.space/d/ORPHA-599507/","orphanet_url":"https://www.orpha.net/en/disease/detail/599507","names":{"fr":{"name":"Déficit acquis en facteur XI"},"de":{"name":"Faktor XI-Mangel, erworbener"},"es":{"name":"Deficiencia del factor XI adquirida"},"it":{"name":"Deficit acquisito del fattore XI","synonyms":["aFXI"]},"nl":{"name":"Verworven deficiëntie van factor XI","synonyms":["aFXI"]},"pt":{"name":"Deficiência de factor XI adquirida"},"pl":{"name":"Nabyty niedobór czynnika XI","synonyms":["aFXI"]},"cs":{"name":"Získaný deficit faktoru XI","synonyms":["aFXI"]},"uk":{"name":"Набутий дефіцит фактора XI","synonyms":["aFXI"]}},"xrefs":[{"source":"ICD-10","code":"D68.4","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"3B2Y","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0035740","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4329257","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10082746","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97992,"name":"Rare hematologic disease"},"parents":[{"orpha":166775,"name":"Rare hemorrhagic disorder due to an acquired coagulation factor defect","classifications":[194]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adolescent","Adult"],"prevalence":[{"type":"Cases/families","qualification":"Case(s)","class":null,"value":15.0,"area":"Worldwide","status":"Validated","source":"18519152[PMID]_29027258[PMID]"},{"type":"Point prevalence","qualification":"Class only","class":"<1 / 1 000 000","value":0.0,"area":"Worldwide","status":"Validated","source":"18519152[PMID]_29027258[PMID]_ORPHANET"}],"phenotypes":null}