{"orpha":59305,"name":"Gestational trophoblastic neoplasm","type":"Clinical group","group":"Group of disorders","status":"active","flags":[],"synonyms":["GTN"],"definition":"A rare, malignant group of gestational trophoblastic diseases always following pregnancy, most often molar pregnancy (hydatidiform mole). Four histological forms are described: invasive mole, gestational choriocarcinoma, placental site trophoblastic tumor (PSTT) and epithelioid trophoblastic tumor (ETT).","note":null,"url":"https://raremap.alftech.space/d/ORPHA-59305/","orphanet_url":"https://www.orpha.net/en/disease/detail/59305","names":{"fr":{"name":"Tumeur trophoblastique gestationnelle","synonyms":["TTG"],"definition":"Formes malignes rares de maladies trophoblastiques gestationnelles se développant toujours après une grossesse, le plus souvent après une grossesse môlaire (môle hydatiforme). Quatre formes histologiques ont été décrites : la môle invasive, le choriocarcinome gestationnel, la tumeur du site d'implantation (TSI) et la tumeur trophoblastique épithélioïde (TTE)."},"de":{"name":"Neoplasie, gestationsbedingte trophoblastische","synonyms":["Schwangerschafts-Trophoblastentumor"],"definition":"Eine seltene Gruppe maligner Trophoblasterkrankungen in der Schwangerschaft, die immer nach einer Schwangerschaft auftreten, am häufigsten nach einer Molarenschwangerschaft (hydatidiforme Mole). Es werden vier histologische Formen beschrieben: invasive Mole, Gestations-Choriokarzinom, trophoblastischer Tumor an der Plazenta (PSTT) und epithelioider trophoblastischer Tumor (ETT)."},"es":{"name":"Neoplasia trofoblástica gestacional","synonyms":["NTG"],"definition":"Es un grupo poco frecuente de enfermedades trofoblásticas gestacionales malignas que suceden al embarazo, con mayor frecuencia después de un embarazo molar (mola hidatiforme). Se describen cuatro formas histológicas: mola invasiva, coriocarcinoma gestacional, tumor trofoblástico del sitio placentario (TTSP) y tumor trofoblástico epitelioide (TTE)."},"it":{"name":"Tumore trofoblastico della gravidanza","synonyms":["GTN"]},"nl":{"name":"Gestationeel trofoblastisch neoplasma","synonyms":["GTN","Gestationele trofoblasttumor"],"definition":"Een zeldzame, maligne groep van gestationele trofoblastziekten die steeds optreden na zwangerschap, meestal mola-zwangerschap (mola hydatidosa). Er werden vier histologische vormen beschreven: invasieve mola, gestationeel choriocarcinoom, trofoblasttumor aan placentabed (PSTT), en epithelioïde trofoblasttumor (ETT)."},"pt":{"name":"Neoplasia trofoblástica gestacional","synonyms":["GTN"],"definition":"Grupo de doenças trofoblásticas gestacionais, raro e maligno que ocorre após a gravidez, mais frequentemente gravidez molar (mola hidatiforme). Quatro formas histológicas são descritas: mola invasiva, coriocarcinoma gestacional, tumor trofoblástico de sítio placentário (PSTT) e tumor trofoblástico epitelióide (TET)."},"pl":{"name":"Ciążowy nowotwór trofoblastyczny","synonyms":["GTN"]},"cs":{"name":"Gestační trofoblastická neoplázie","synonyms":["GTN"]},"uk":{"name":"Гестаційне трофобластичне новоутворення","synonyms":["GTN"],"definition":"A rare, malignant group of gestational trophoblastic diseases always following pregnancy, most often molar pregnancy (hydatidiform mole). Four histological forms are described: invasive mole, gestational choriocarcinoma, placental site trophoblastic tumor (PSTT) and epithelioid trophoblastic tumor (ETT)."},"zh":{"name":"妊娠滋养细胞肿瘤","synonyms":["GTN"]},"tr":{"name":"Gestasyonel trofoblastik neoplazm","synonyms":["GTN"]}},"xrefs":[{"source":"ICD-11","code":"2C75.0","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1972855304"},{"source":"MONDO","code":"0018944","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"18944","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C1135868","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"6498","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10061988","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":254685,"name":"Gestational trophoblastic disease","classifications":[202,205]}],"children":[{"orpha":254698,"name":"Epithelioid trophoblastic tumor","type":"Disease"},{"orpha":99926,"name":"Gestational choriocarcinoma","type":"Disease"},{"orpha":99925,"name":"Invasive mole","type":"Disease"},{"orpha":99928,"name":"Placental site trophoblastic tumor","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adult"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"},{"type":"Annual incidence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":null}