{"orpha":56044,"name":"Carcinoma of gallbladder and extrahepatic biliary tract","type":"Clinical group","group":"Group of disorders","status":"active","flags":[],"synonyms":["Carcinoma of gallbladder and EBT"],"definition":"Carcinoma of the gallbladder (GBC) is the most common and aggressive form of biliary tract cancer (BTC) usually arising in the fundus of the gallbladder, rapidly metastasizing to lymph nodes and distant sites.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-56044/","orphanet_url":"https://www.orpha.net/en/disease/detail/56044","names":{"fr":{"name":"Carcinome de la vésicule biliaire et des voies biliaires extrahépatiques","synonyms":["Carcinome de la vésicule biliaire et des VBEH"],"definition":"Le carcinome de la vésicule biliaire (CVB) est la forme la plus commune et la plus agressive de cancer des voies biliaires. Il survient généralement au fond de la vésicule biliaire, avec des métastases d'apparition rapide dans les ganglions lymphatiques et les zones distantes."},"de":{"name":"Karzinom der Gallenblase und der extrahepatischen Gallengänge","synonyms":["GBC","Gallenblasen- und EBT-Karzinom"],"definition":"Das Gallenblasenkarzinom (GBC) ist die häufigste und aggressivste Form des Gallengangkrebses (siehe dort) und entsteht in der Regel im Fundus der Gallenblase und metastasiert rasch in die Lymphknoten und entfernte Stellen."},"es":{"name":"Carcinoma de vesícula y vías biliares extrahepáticas","synonyms":["Carcinoma de vesícula y VBE","GBC"],"definition":"El carcinoma de la vesícula biliar (GBC) es la forma más frecuente y agresiva de los tumores del conducto biliar (BTC). En general se origina en el fondo de la vesícula biliar, produciéndose rápidamente metástasis a los ganglios linfáticos y órganos distantes."},"it":{"name":"Carcinoma della cistifellea e delle vie biliari extraepatiche","synonyms":["Carcinoma della cistifellea e delle VBE","GBC"],"definition":"Il carcinoma della colecisti (GBC) è la forma più comune e aggressiva di cancro del tratto biliare (BTC); di solito insorge nel fondo della colecisti e metastatizza rapidamente verso i linfonodi e i siti distanti."},"nl":{"name":"Carcinoom van galblaas en extrahepatische galwegen","synonyms":["Carcinoom van galblaas en EBT","GBC"],"definition":"Galblaascarcinoom (GBC) is de meest voorkomende en agressieve vorm van galwegkanker (BTC, zie deze term), dat meestal ontstaat in de galblaasfundus en snel uitzaait naar lymfeklieren en verdere locaties."},"pt":{"name":"Carcinoma da vesícula biliar"},"pl":{"name":"Rak pęchrzyka żółciowego i zewnątrzwątrobowych przewodów żółciowych","synonyms":["GBC","Rak pęchrzyka żółciowego i EBT"]},"cs":{"name":"Karcinom žlučníku a extrahepatických žlučových cest","synonyms":["Karcinom žlučníku a EBT"]},"uk":{"name":"Карцинома жовчного міхура та позапечінкових жовчовивідних шляхів","synonyms":["Карцинома жовчного міхура та ЕБТ"],"definition":"Carcinoma of the gallbladder (GBC) is the most common and aggressive form of biliary tract cancer (BTC; see this term) usually arising in the fundus of the gallbladder, rapidly metastasizing to lymph nodes and distant sites."},"zh":{"name":"胆囊癌和肝外胆管癌","synonyms":["胆囊癌和EBT癌"]},"tr":{"name":"Safra kesesi karsinomu ve ekstrahepatik safra yolları","synonyms":["Safra kesesi karsinomu ve EBT"]}},"xrefs":[{"source":"MONDO","code":"0018918","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"18918","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5566557","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10007426","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":306633,"name":"Rare tumor of gallbladder and extrahepatic biliary tract","classifications":[183,202]}],"children":[{"orpha":424991,"name":"Adenocarcinoma of the gallbladder and extrahepatic biliary tract","type":"Disease"},{"orpha":70567,"name":"Cholangiocarcinoma","type":"Disease"},{"orpha":529852,"name":"Combined hepatocellular carcinoma and cholangiocarcinoma","type":"Disease"},{"orpha":99978,"name":"Perihilar cholangiocarcinoma","type":"Disease"},{"orpha":424996,"name":"Squamous cell carcinoma of gallbladder and extrahepatic biliary tract","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adult"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"1-5 / 10 000","value":12.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":5.3,"area":"Japan","status":"Not yet validated","source":"ORPHANET"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":1.5,"area":"United States","status":"Not yet validated","source":"13835134[PMID]_17857545[PMID]_13425293[PMID]_22570746[PMID]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-5 / 10 000","value":14.0,"area":"Poland","status":"Validated","source":"16397865[PMID]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":1.27,"area":"France","status":"Not yet validated","source":"10951337[PMID]"},{"type":"Point prevalence","qualification":"Class only","class":"1-5 / 10 000","value":0.0,"area":"Europe","status":"Not yet validated","source":"ORPHANET"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":4.37,"area":"Europe","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"}],"phenotypes":null}