{"orpha":558411,"name":"Idiopathic gastroparesis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare idiopathic gastroesophageal disease characterized by delayed gastric emptying in the absence of mechanical obstruction of the gastric outlet. Patients present symptoms including nausea, vomiting, early satiety, postprandial fullness, bloating, abdominal pain and, in more severe cases, dehydration, electrolyte disturbances, weight loss and malnutrition.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-558411/","orphanet_url":"https://www.orpha.net/en/disease/detail/558411","names":{"fr":{"name":"Gastroparésie idiopathique","definition":"Maladie gastro-oesophagienne idiopathique rare caractérisée par un retard de la vidange gastrique en l'absence d'obstruction mécanique de la sortie gastrique. Les patients manifestent des symptômes tels que des nausées, des vomissements, une satiété précoce, une plénitude postprandiale, des ballonnements, des douleurs abdominales et, dans les cas les plus sévères, une déshydratation, des troubles électrolytiques, une perte de poids et une malnutrition."},"de":{"name":"Gastroparese, idiopathische","definition":"Eine seltene idiopathische gastroösophageale Erkrankung, die durch eine verzögerte Magenentleerung gekennzeichnet ist, ohne dass eine mechanische Obstruktion des Magenausgangs vorliegt. Die Patienten zeigen Symptome wie Übelkeit, Erbrechen, frühzeitige Sättigung, postprandiales Völlegefühl, Blähungen, Bauchschmerzen und in schwereren Fällen Dehydrierung, Elektrolytstörungen, Gewichtsverlust und Unterernährung."},"es":{"name":"Gastroparesia idiopática","definition":"Es una enfermedad gastroesofágica idiopática poco frecuente caracterizada por retraso del vaciamiento gástrico en ausencia de obstrucción mecánica de la salida gástrica. Los pacientes presentan síntomas que incluyen náuseas, vómitos, saciedad precoz, plenitud posprandial, hinchazón, dolor abdominal y, en casos más graves, deshidratación, alteraciones electrolíticas, pérdida ponderal y desnutrición."},"it":{"name":"Gastroparesi idiopatica","definition":"Si tratta di una malattia gastroesofagea idiopatica rara, caratterizzata da ritardo dello svuotamento gastrico, in assenza di ostruzioni meccaniche del tratto inferiore dello stomaco. I pazienti presentano nausea, vomito, immediata sazietà, senso di pienezza postprandiale, gonfiore, dolore addominale e, nei casi più gravi, disidratazione, squilibrio elettrolitico, perdita di peso e malnutrizione."},"nl":{"name":"Idiopathische gastroparese","definition":"Een zeldzame, idiopathische gastro-oesofageale aandoening, gekarakteriseerd door vertraagde lediging van maag zonder aanwezigheid van mechanische obstructie van maaguitgang. Patiënten vertonen symptomen waaronder misselijkheid, braken, vroegtijdige verzadiging, vol gevoel na eten, gezwollen abdomen, abdominale pijn en, in ernstigere gevallen, dehydratie, verstoorde elektrolytenevenwicht, gewichtsverlies, en malnutritie."},"pt":{"name":"Gastroparésia idiopática"},"pl":{"name":"Gastropareza idiopatyczna"},"cs":{"name":"Idiopatická gastroparéza"},"uk":{"name":"Ідіопатичний гастропарез","definition":"A rare idiopathic gastroesophageal disease characterized by delayed gastric emptying in the absence of mechanical obstruction of the gastric outlet. Patients present symptoms including nausea, vomiting, early satiety, postprandial fullness, bloating, abdominal pain and, in more severe cases, dehydration, electrolyte disturbances, weight loss and malnutrition."},"zh":{"name":"特发性胃肌轻瘫","definition":"一种罕见的特发性胃食管疾病，以胃出口无机械性梗阻时胃排空延迟为特征。患者出现的症状包括恶心、呕吐、早饱、餐后饱胀、腹胀、腹痛，更严重的情况下还会出现脱水、电解质紊乱、体重减轻和营养不良。"},"tr":{"name":"İdiyopatik gastroparezi"}},"xrefs":[{"source":"ICD-10","code":"K31.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"DA41.00","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"598423727"},{"source":"MONDO","code":"0034150","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0267171","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97935,"name":"Rare gastroenterologic disease"},"parents":[{"orpha":101936,"name":"Rare gastroesophageal disease","classifications":[152]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adolescent","Adult","Childhood","Elderly","Infancy"],"prevalence":[{"type":"Point prevalence","qualification":"Value and class","class":"1-5 / 10 000","value":11.4,"area":"Specific population","status":"Validated","source":"ORPHANET_30396519[PMID]"}],"phenotypes":null}