{"orpha":54368,"name":"Sarcocystosis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Sarcosporidiosis"],"definition":"A rare parasitic disease characterized by infection with sarcocystis species with humans as definitive (intestinal sarcocystosis) or aberrant intermediate (muscular sarcocystosis with development of sarcocysts in myocytes of skeletal, cardiac, and smooth muscle) host. Enteric infection is often mild or asymptomatic but may cause symptomatic enteritis with nausea, abdominal pain, diarrhea, and vomiting. Symptoms of muscular sarcocystosis include fever, fatigue, headache, cough, myalgia, and arthralgia, among others, with the possibility of a long-lasting, waxing and waning course.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-54368/","orphanet_url":"https://www.orpha.net/en/disease/detail/54368","names":{"fr":{"name":"Sarcocystose","synonyms":["Sarcosporidiose"],"definition":"Parasitose rare caractérisée par une infection due aux espèces du genre <i>Sarcocystis</i>, dont les humains sont les hôtes définitifs (sarcocystose intestinale) ou les hôtes intermédiaires accidentels (sarcocystose musculaire avec développement de sarcocystes dans les myocytes des muscles squelettiques, cardiaques et lisses). L'infection entérique est souvent légère ou asymptomatique, mais elle peut causer une entérite symptomatique se manifestant par des nausées, des douleurs abdominales, des diarrhées et des vomissements. Parmi les symptômes de la sarcocystose musculaire, qui peuvent être durables et fluctuer au fil du temps, figurent fièvre, fatigue, céphalées, toux, myalgie et arthralgie."},"de":{"name":"Sarkozystose","synonyms":["Sarkosporidiose"],"definition":"Eine seltene parasitäre Erkrankung, die durch eine Infektion mit Protozoen der Gattung <i>Sarcocystis</i> gekennzeichnet ist, mit dem Menschen als Endwirt (intestinale Sarkozystose) oder als abweichendem Zwischenwirt (muskuläre Sarkozystose mit Entwicklung von Sarkozysten in Myozyten der Skelett-, Herz- und glatten Muskulatur). Die enterale Infektion verläuft häufig mild oder asymptomatisch, kann aber auch zu einer symptomatischen Enteritis mit Übelkeit, Bauchschmerzen, Durchfall und Erbrechen führen. Zu den Symptomen der muskulären Sarkozystose gehören Fieber, Müdigkeit, Kopfschmerzen, Husten, Myalgien und Arthralgien, wobei ein protrahierter Verlauf möglich ist."},"es":{"name":"Sarcocistosis","synonyms":["Sarcosporidiosis"],"definition":"Es una enfermedad parasitaria poco frecuente caracterizada por una infección por especies de Sarcocystis en la que los humanos constituyen el hospedador definitivo (sarcocistosis intestinal) o intermediario aberrante (sarcocistosis muscular con desarrollo de sarcoquistes en los miocitos del músculo esquelético, cardíaco y liso). La infección entérica suele ser leve o asintomática, aunque puede causar enteritis sintomática con náuseas, dolor abdominal, diarrea y vómitos. Los síntomas de la sarcocistosis muscular incluyen fiebre, cansancio, cefalea, tos, mialgia y artralgia, entre otros, con la posibilidad de un curso cambiante de larga duración."},"it":{"name":"Sarcocistosi","synonyms":["Sarcosporidiosi"],"definition":"Si tratta di una parassitosi rara causata dalla specie dei sarcocisti, che infetta l'uomo come ospite definitivo (sarcocistosi intestinale) o intermedio aberrante (sarcocistosi muscolare associata allo sviluppo di sarcocisti nei miociti dei muscoli scheletrici e lisci, e del cuore). L'infezione intestinale è spesso lieve o asintomatica, ma può causare un'enterite sintomatica con nausea, dolore addominale, diarrea e vomito. I sintomi della sarcocistosi muscolare comprendono la febbre, l'affaticamento, la cefalea, la tosse, la mialgia e l'artralgia; la malattia può avere un decorso lungo e altalenante."},"nl":{"name":"Sarcocystose","synonyms":["Sarcosporidiose"],"definition":"Een zeldzame parasitaire ziekte, gekarakteriseerd door infectie met soorten van het geslacht <i>Sarcocystis</i>, waarbij mensen fungeren als definitieve gastheer (intestinale sarcocystose) of als atypische tussengastheer (musculaire sarcocystose met ontwikkeling van sarcocysten in myocyten van skelet-, hart-, en gladde spier). Enterische infectie is vaak mild of asymptomatisch, maar kan symptomatische enteritis met misselijkheid, abdominale pijn, diarree en braken veroorzaken. Symptomen van musculaire sarcocystose zijn onder meer koorts, vermoeidheid, hoofdpijn, hoest, myalgie, en artralgie, met mogelijk een langdurig verloop met opflakkeringen."},"pt":{"name":"Sarcocistose","synonyms":["Sarcosporidiose"]},"pl":{"name":"Sarkocystoza","synonyms":["Sarkosporidioza"]},"cs":{"name":"Sarkocystóza","synonyms":["Sarcosporidióza"]},"uk":{"name":"Саркоцистоз","synonyms":["Саркоспоридіоз"],"definition":"A rare parasitic disease characterized by infection with sarcocystis species with humans as definitive (intestinal sarcocystosis) or aberrant intermediate (muscular sarcocystosis with development of sarcocysts in myocytes of skeletal, cardiac, and smooth muscle) host. Enteric infection is often mild or asymptomatic but may cause symptomatic enteritis with nausea, abdominal pain, diarrhea, and vomiting. Symptoms of muscular sarcocystosis include fever, fatigue, headache, cough, myalgia, and arthralgia, among others, with the possibility of a long-lasting, waxing and waning course."},"zh":{"name":"肉孢子虫病","synonyms":["肉孢子虫病"]},"tr":{"name":"Sarkosistoz","synonyms":["Sarkosporidiyoz"]}},"xrefs":[{"source":"ICD-10","code":"A07.8","qualifier":"NTBT","icd_relation":"inclusion","validated":true},{"source":"ICD-11","code":"1A34","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"261748740"},{"source":"MONDO","code":"0018903","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D012523","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0036231","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10039483","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":163588,"name":"Rare parasitic disease","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}