{"orpha":525,"name":"Lichen planopilaris","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Follicular lichen planus","LPP","Lichen follicularis","Lichen planus follicularis"],"definition":"A rare cutaneous variant of lichen planus which affects hair follicles. It may occur on its own or in association with more common forms of lichen planus, usually classical type and/or oral lichen planus.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-525/","orphanet_url":"https://www.orpha.net/en/disease/detail/525","names":{"fr":{"name":"Lichen plan pilaire","synonyms":["LPP","Lichen plan folliculaire"],"definition":"Le lichen plan pilaire (LPP) est une variété cutanée rare de lichen plan qui touche les follicules pileux. Il peut apparaître seul ou associé à des formes plus fréquentes de lichen plan, en général classiques et/ou buccales."},"de":{"name":"Lichen planopilaris","synonyms":["LPP","Lichen follicularis","Lichen planus follicularis","Lichen planus, follikulärer"],"definition":"Der Lichen Planopilaris (LPP) ist eine seltene kutane Variante des Lichen Planus (s. dort) mit Veränderungen der Haarfolikel. Er kann in dieser Form isoliert oder assoziiert mit häufigeren Formen des Lichen Planus auftreten, in der Regel dem klassischen Typ und/oder dem oralen Lichen Planus."},"es":{"name":"Liquen plano pilar","synonyms":["Liquen folicular plano","Liquen plano pilaris","Liquen folicular"],"definition":"Es una variante cutánea rara de liquen plano con afectación preferente de los folículos pilosos. Puede ocurrir aislado o asociado a formas más frecuentes de liquen plano, por lo general, con el tipo clásico y/o con el liquen plano oral."},"it":{"name":"Lichen planus pilare","synonyms":["LPP","Lichen follicolare","Lichen planus follicolare","Lichen planus follicularis"]},"nl":{"name":"Lichen planopilaris","synonyms":["Folliculaire lichen planus","LPP","Lichen follicularis","Lichen planus follicularis"],"definition":"Een zeldzame, cutane variant van lichen planus die haarfollikels aantast. Het kan op zichzelf voorkomen of in associatie met meer gangbare vormen van lichen planus, meestal het klassieke type en/of orale lichen planus."},"pt":{"name":"Líquen plano folicular","definition":"Variante cutânea rara do líquen plano que afeta os folículos pilosos. Pode ocorrer isoladamente ou em associação com formas mais comuns de líquen plano, geralmente do tipo clássico e/ou líquen plano oral."},"pl":{"name":"Liszaj płaski mieszkowy","synonyms":["LPP"]},"cs":{"name":"Lichen planopilaris","synonyms":["Folikulární lichen planus","LPP","Lichen follicularis","Lichen planus follicularis"]},"uk":{"name":"Лишай плоский (Lichen planopilaris)","synonyms":["Фолікулярний плоский лишай","Фолікулярний лишай (Lichen follicularis)","Плоский лишай фолікулярний","LPP"],"definition":"A rare cutaneous variant of lichen planus which affects hair follicles. It may occur on its own or in association with more common forms of lichen planus, usually classical type and/or oral lichen planus."},"zh":{"name":"毛囊扁平苔癣","synonyms":["毛发扁平苔藓"]},"tr":{"name":"Liken planopilar","synonyms":["LPP","Liken follikülaris","Folliküler liken planus","Liken planus follikülaris"]}},"xrefs":[{"source":"ICD-10","code":"L66.1","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"EA91.2","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"572258139"},{"source":"MONDO","code":"0018879","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"C535892","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0023645","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"3247","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10081142","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":89826,"name":"Rare skin disease"},"parents":[{"orpha":79364,"name":"Alopecia","classifications":[187]},{"orpha":254370,"name":"Rare cutaneous lichen planus","classifications":[187]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adult"],"prevalence":[{"type":"Cases/families","qualification":"Case(s)","class":null,"value":300.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2016-06-01","source":null,"terms":[{"hpo":"HP:0001596","label":"Alopecia","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0000962","label":"Hyperkeratosis","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0100725","label":"Lichenification","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0200034","label":"Papule","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001231","label":"Abnormal fingernail morphology","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0004334","label":"Dermal atrophy","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000989","label":"Pruritus","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0200042","label":"Skin ulcer","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0008066","label":"Abnormal blistering of the skin","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002242","label":"Abnormal intestine morphology","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012115","label":"Hepatitis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001053","label":"Hypopigmented skin patches","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100649","label":"Neoplasm of the oral cavity","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001806","label":"Onycholysis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001059","label":"Pterygium","frequency":"Occasional (29-5%)","criteria":null}]}}