{"orpha":51890,"name":"Anterior cutaneous nerve entrapment syndrome","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["ACNES","Intercostal nerve syndrome","Rectus abdominis syndrome"],"definition":"A chronic neuropathic pain syndrome of the abdominal wall caused by entrapment of anterior cutaneous branches of 7 to 12th intercostal nerves along the lateral border of the anterior rectus abdominis fascia causing severe pain and tenderness of the involved dermatome.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-51890/","orphanet_url":"https://www.orpha.net/en/disease/detail/51890","names":{"fr":{"name":"Syndrome rectus abdominis","synonyms":["ACNES","Syndrome du nerf intercostal"],"definition":"Syndrome douloureux neuropathique chronique de la paroi abdominale causé par la compression des branches cutanées antérieures des nerfs intercostaux entre la 7<sup>e</sup> et la 12<sup>e</sup> vertèbre dorsale, le long du bord latéral du fascia du droit antérieur de l'abdomen, provoquant une douleur intense et une sensibilité du dermatome concerné."},"de":{"name":"Kómár-Syndrom","synonyms":["Intercostalnerven-Syndrom","Rectus abdominis-Syndrom"]},"es":{"name":"Síndrome de atrapamiento del nervio cutáneo anterior","synonyms":["Síndrome de Komar"],"definition":"Es un síndrome de dolor neuropático crónico a nivel de la pared abdominal causado por el atrapamiento de las ramas anteriores terminales de los nervios intercostales T7 a T12 a lo largo del borde lateral de la fascia del recto del abdomen ocasionando dolor intenso y sensibilidad en el dermatoma afectado."},"it":{"name":"Sindrome da intrappolamento del nervo cutaneo anteriore","synonyms":["Sindrome del muscolo retto dell'addome","Sindrome del nervo intercostale"],"definition":"La sindrome da intrappolamento del nervo cutaneo anteriore (ACNES) è una sindrome da dolore neuropatico cronico della parete addominale, causata dall'intrappolamento dei rami cutanei anteriori dei nervi intercostali da 7 a 12 lungo il bordo laterale della fascia anteriore del retto addominale, che causa forte dolore e ipersensibilità del dermatoma interessato."},"nl":{"name":"Syndroom van Kómár","synonyms":["ACNES","Abdominale intercostale neuralgie","Beklemming van de anterieure tak van een intercostale zenuw","Buikwandpijnsyndroom","Intercostale zenuw-syndroom","Rectus abdominis-syndroom"],"definition":"Een chronisch, neuropathisch buikwandpijnsyndroom, veroorzaakt door beknelling van anterieure huidtakjes van de 7de tot 12de intercostale zenuwen langs de laterale grens van de voorste fascie van de rectus abdominis (rechte buikspier), wat leidt tot hevige pijn en gevoeligheid van het betrokken dermatoom."},"pt":{"name":"Síndrome de Komar","synonyms":["Síndrome dos nervos intercostais","Síndrome rectos abdominais"]},"pl":{"name":"Zespół Komara","synonyms":["Zespół mięśnia prostego brzucha","Zespół nerwu międzyżebrowego"]},"cs":{"name":"Entrapment syndrom předních větví kožních nervů","synonyms":["ACNES","Rectus abdominis syndrome","Intercostal nerve syndrome"]},"uk":{"name":"Синдром защемлення переднього шкірного нерва","synonyms":["ACNES","Синдром міжреберного нерва","Синдром прямих мязів живота"],"definition":"A chronic neuropathic pain syndrome of the abdominal wall caused by entrapment of anterior cutaneous branches of 7 to 12th intercostal nerves along the lateral border of the anterior rectus abdominis fascia causing severe pain and tenderness of the involved dermatome."},"zh":{"name":"前皮神经卡压综合征","synonyms":["肋间神经综合症"]},"tr":{"name":"Anterior kutanöz sinir tuzak sendromu","synonyms":["ACNES","Rektus abdominis sendromu","İnterkostal sinir sendromu"]}},"xrefs":[{"source":"ICD-10","code":"G58.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"8E43.Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"922856471"},{"source":"MONDO","code":"0018873","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0393899","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":182086,"name":"Acquired peripheral neuropathy","classifications":[181]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"},{"type":"Annual incidence","qualification":"Value and class","class":"6-9 / 10 000","value":55.6,"area":"Netherlands","status":"Validated","source":"[EXPERT]_25887961[PMID]_72957[PMID]"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2019-11-06","source":"24197667[PMID]_30817351[PMID]_29270882[PMID]_29516161[PMID]","terms":[{"hpo":"HP:0002027","label":"Abdominal pain","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0010830","label":"Impaired tactile sensation","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0003474","label":"Somatic sensory dysfunction","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0000975","label":"Hyperhidrosis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002321","label":"Vertigo","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0003270","label":"Abdominal distention","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012533","label":"Allodynia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002039","label":"Anorexia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0003418","label":"Back pain","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0003565","label":"Elevated erythrocyte sedimentation rate","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100963","label":"Hyperesthesia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001974","label":"Increased total leukocyte count","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002018","label":"Nausea","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0004325","label":"Decreased body weight","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0000023","label":"Inguinal hernia","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0004798","label":"Recurrent infection of the gastrointestinal tract","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0000010","label":"Recurrent urinary tract infections","frequency":"Very rare (<4-1%)","criteria":null}]}}