{"orpha":506207,"name":"Rare disorder potentially indicated for transplant","type":"Category","group":"Group of disorders","status":"active","flags":[],"synonyms":[],"definition":"A group of rare disorders with irreversible organ and/or system dysfunction(s), or the effects of dysfunction after alternative medical and surgical treatments have been utilized, for which the benefits of transplantation outweigh the risk of continuing alternative modalities.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-506207/","orphanet_url":"https://www.orpha.net/en/disease/detail/506207","names":{"fr":{"name":"Maladie rare possiblement indiquée pour une transplantation","definition":"Groupe de maladies rares caractérisées par un ou plusieurs dysfonctionnements irréversibles d'un organe et/ou d'un système d'organes, ou par les effets d'un dysfonctionnement à la suite de l'administration de traitements médicaux et chirurgicaux, dans un contexte dans lequel les bénéfices de la transplantation l'emportent sur le risque de la poursuite des traitements alternatifs."},"de":{"name":"Seltene Krankheit zur potentiellen Transplantation indiziert","definition":"Eine Gruppe seltener Erkrankungen mit irreversibler Organ- und/oder Systemdysfunktion(en) oder den Auswirkungen einer Dysfunktion nach Anwendung alternativer medizinischer und chirurgischer Behandlungen, bei denen der Nutzen einer Transplantation das Risiko der Fortführung alternativer Modalitäten überwiegt."},"es":{"name":"Trastorno raro potencialmente indicado para trasplante","definition":"Es un grupo poco frecuente de trastornos caracterizados por insuficiencia irreversible de órganos y/o sistemas orgánicos, o que presentan insuficiencia después de haberse sometido a tratamientos médicos y quirúrgicos alternativos, para los cuales el beneficio de un trasplante supera el riesgo de continuar con dichos tratamientos alternativos."},"it":{"name":"Malattia rara con potenziale indicazione al trapianto","definition":"Comprende un gruppo di malattie rare, caratterizzate da una o più disfunzioni irreversibili di organi e/o apparati, o che sono secondarie ad una disfunzione correlata a trattamenti medici e chirurgici alternativi, per le quali i benefici del trapianto sono superiori ai rischi del proseguimento delle terapie alternative."},"nl":{"name":"Zeldzame aandoening mogelijk geïndiceerd voor transplantatie","definition":"Een groep van zeldzame aandoeningen met onomkeerbare orgaan- en/of systeemdisfunctie(s), of de effecten van disfunctie nadat alternatieve medische en chirurgische behandelingen werden benut, waarvoor de voordelen van transplantatie opwegen tegen het risico van de voortzetting van alternatieve modaliteiten."},"pt":{"name":"Doença rara com potencial indicação para transplante"},"pl":{"name":"Rzadka choroba, będąca potencjalnym wskazaniem do przeszczepu","definition":"Grupa rzadkich zaburzeń charakteryzujących się nieodwracalną dysfunkcją(-ami) narządów i/lub układów lub skutkami takich dysfunkcji po zastosowaniu alternatywnych metod leczenia i zabiegów chirurgicznych, w przypadku których korzyści z przeszczepienia przewyższają ryzyko kontynuowania alternatywnych metod leczenia."},"cs":{"name":"Vzácná porucha indikovaná k transplantaci"},"uk":{"name":"Рідкісне захворювання, що є потенційним показанням для трансплантації","definition":"A group of rare disorders with irreversible organ and/or system dysfunction(s), or the effects of dysfunction after alternative medical and surgical treatments have been utilized, for which the benefits of transplantation outweigh the risk of continuing alternative modalities."},"zh":{"name":"可能需要移植的罕见疾病","definition":"一组罕见的疾病，具有不可逆转的器官和（或）系统功能障碍，或在使用替代性医疗和手术治疗后功能障碍，移植的好处大于继续替代治疗的风险。"},"tr":{"name":"Organ nakli gerektirebilen nadir hastalık"}},"xrefs":[{"source":"UMLS","code":"C5681217","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":null,"parents":[{"orpha":565779,"name":"Rare disorder potentially indicated for transplant or complication after transplantation","classifications":[233]}],"children":[{"orpha":506216,"name":"Rare disorder potentially indicated for bowel transplant","type":"Category"},{"orpha":506225,"name":"Rare disorder potentially indicated for heart transplant","type":"Category"},{"orpha":506219,"name":"Rare disorder potentially indicated for hematopoietic stem cell transplant","type":"Category"},{"orpha":506213,"name":"Rare disorder potentially indicated for kidney transplant","type":"Category"},{"orpha":506210,"name":"Rare disorder potentially indicated for liver transplant","type":"Category"},{"orpha":506222,"name":"Rare disorder potentially indicated for lung transplant","type":"Category"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}