{"orpha":499,"name":"Kerion celsi","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare inflammatory and suppurating type of tinea capitis, a skin infection caused by <i>Trichophyton</i> or <i>Microsporum</i> fungi, that predominantly affects the scalp and that is characterized by the development of painful crusty lesions covered with follicular pustules and surrounded by erythematous alopecic areas, that can later evolve into abscesses and leave permanent cicatricial alopecia. Lesions can be associated with regional lymphadenopathy.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-499/","orphanet_url":"https://www.orpha.net/en/disease/detail/499","names":{"fr":{"name":"Kérion de Celse","definition":"Le kérion de Celse est une teigne inflammatoire et suppurative rare du cuir chevelu, une infection cutanée causée par les champignons <i>Trichophyton</i> ou <i>Microsporum</i>. Il affecte surtout le cuir chevelu, et se caractérise par le développement de lésions croûteuses douloureuses recouvertes par des pustules folliculaires et entourées par des zones alopéciques érythémateuses pouvant évoluer vers des abcès et laisser une alopécie cicatricielle permanente. Les lésions peuvent être associées à une lymphadénopathie régionale."},"de":{"name":"Kerion Celsi","definition":"Eine seltene entzündliche und eiternde Form der Tinea capitis, einer durch <I>Trichophyton</I>- oder <I>Microsporum</I>-Pilze verursachten Hautinfektion, die vorwiegend die Kopfhaut betrifft und durch die Entwicklung schmerzhafter, krustiger Läsionen gekennzeichnet ist, die mit follikulären Pusteln bedeckt und von erythematösen alopezischen Bereichen umgeben sind, die sich später zu Abszessen entwickeln und eine dauerhafte narbige Alopezie hinterlassen können. Die Läsionen können mit einer regionalen Lymphadenopathie einhergehen."},"es":{"name":"Querión de Celso","definition":"Es un tipo supurativo e inflamatorio poco frecuente de tiña capitis, una infección de la piel causada por hongos del género <i>Trichophyton</i> o <i>Microsporum</i>, que afecta predominantemente al cuero cabelludo y que se caracteriza por el desarrollo de dolorosas lesiones costrosas con pústulas foliculares, rodeadas de áreas de alopecia eritematosa, que pueden evolucionar más tarde en abscesos y dejar una alopecia cicatricial permanente. Las lesiones pueden estar asociadas a una linfadenopatía regional."},"it":{"name":"Kerion celsi","definition":"Il Kerion Celsi è una manifestazione infiammatoria e suppurativa rara della tinea capitis, un'infezione cutanea causata da funghi del genere Trichophyton o Microsporum, che interessa prevalentemente il cuoio capelluto e si caratterizza per lo sviluppo di lesioni crostose dolorose ricoperte di pustole follicolari, circondate da aree alopeciche eritematose, che possono evolvere in ascessi ed esitare in un'alopecia cicatriziale permanente. Le lesioni possono associarsi a linfoadenopatie regionali."},"nl":{"name":"Kerion celsi","synonyms":["Tinea kerion"],"definition":"Een zeldzaam, inflammatoir en suppuratief type van tinea capitis, een huidinfectie veroorzaakt door de fungus <i>Trichophyton</i> of <i>Microsporum</i>, dat voornamelijk de hoofdhuid aantast en dat gekarakteriseerd wordt door de ontwikkeling van pijnlijke, korstige letsels die zijn bedekt met folliculaire pustels en omringd door erythemateuze kale gebieden, en die later kunnen evolueren tot abcessen en permanente cicatriciële alopecie kunnen achterlaten. Letsels kunnen geassocieerd zijn met regionale lymfadenopathie."},"pt":{"name":"Kerion celsi"},"pl":{"name":"Grzybica owłosionej skóry głowy ze stanem zapalnym"},"cs":{"name":"Kerion celsi"},"uk":{"name":"Керіон (Kerion celsi)","definition":"A rare inflammatory and suppurating type of tinea capitis, a skin infection caused by <i>Trichophyton</i> or <i>Microsporum</i> fungi, that predominantly affects the scalp and that is characterized by the development of painful crusty lesions covered with follicular pustules and surrounded by erythematous alopecic areas, that can later evolve into abscesses and leave permanent cicatricial alopecia. Lesions can be associated with regional lymphadenopathy."},"zh":{"name":"塞耳斯脓癣"},"tr":{"name":"Kerion celsi"}},"xrefs":[{"source":"ICD-10","code":"B35.0","qualifier":"NTBT","icd_relation":"index","validated":true},{"source":"ICD-11","code":"1F28.4","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1449494917"},{"source":"MONDO","code":"0010146","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0276742","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"3109","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":89826,"name":"Rare skin disease"},"parents":[{"orpha":90077,"name":"Other acquired skin disease","classifications":[187]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2016-06-01","source":null,"terms":[{"hpo":"HP:0011123","label":"Inflammatory abnormality of the skin","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0100838","label":"Recurrent cutaneous abscess formation","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001581","label":"Recurrent skin infections","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001596","label":"Alopecia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001945","label":"Fever","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002716","label":"Lymphadenopathy","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002076","label":"Migraine","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0003326","label":"Myalgia","frequency":"Occasional (29-5%)","criteria":null}]}}