{"orpha":498700,"name":"OBSOLETE: Limbic encephalitis with neurexin-3 antibodies","type":"Disease","group":"Disorder","status":"inactive","flags":["Obsolete entity"],"synonyms":[],"definition":null,"note":"This entity has been obsoleted from the Orphanet nomenclature of rare diseases.<br/><br/>Instead, consider using Autoimmune encephalitis","url":"https://raremap.alftech.space/d/ORPHA-498700/","orphanet_url":"https://www.orpha.net/en/disease/detail/498700","names":{"fr":{"name":"OBSOLETE : Encéphalite limbique avec anticorps neurexine-3"},"de":{"name":"OBSOLET: Limbische Enzephalitis mit Neurexin-3-Antikörper"},"es":{"name":"OBSOLETO: Encefalitis límbica con anticuerpos neurexina-3"},"it":{"name":"OBSOLETO: Encefalite limbica con anticorpi anti-neuressina 3"},"nl":{"name":"OBSOLEET: Limbische encefalitis met neurexine-3 antilichamen"},"pt":{"name":"OBSOLETO: Encefalite límbica com anticorpos neurexina-3"},"pl":{"name":"NIEAKTUALNE: Zapalenie limbiczne mózgu z przeciwciałami neureksyny 3"},"cs":{"name":"NEAKTUÁLNÍ: Limbická encefalitida s protilátkami proti neurexinu 3"},"uk":{"name":"ЗАСТАРІЛО: Лімбічний енцефаліт з антитілами до нейрексину-3"},"zh":{"name":"边缘叶脑炎合并神经毒素3抗体","definition":"一种罕见的非癌旁的边缘叶脑炎，其特征是一种严重但能治疗的自身免疫性脑炎，与抗神经素-3α的自身抗体有关。患者出现前期发热、头痛或胃肠道症状，随后迅速发展为神志不清、癫痫发作和意识水平下降。部分患者可能出现轻度口面运动障碍，以及危及生命的并发症，如中枢性通气不足，需要呼吸支持。"},"tr":{"name":"Nöreksin-3 antikorları ile seyreden limbik ensefalit"}},"xrefs":[],"associations":[{"type":"Referred to","orpha":622014,"name":"Autoimmune encephalitis"}],"incoming_associations":[],"preferential_parent":null,"parents":[],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}