{"orpha":482072,"name":"HTRA1-related cerebral small vessel disease","type":"Clinical group","group":"Group of disorders","status":"active","flags":[],"synonyms":["HTRA1-related cerebral angiopathy"],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-482072/","orphanet_url":"https://www.orpha.net/en/disease/detail/482072","names":{"fr":{"name":"Maladie des petites artères cérébrales associée à HTRA1","synonyms":["Angiopathie cérébrale associée à HTRA1"]},"de":{"name":"Zerebrale Mikroangiopathie, HTRA1-abhängige","synonyms":["Angiopathie, zerebrale, HTRA1-abhängige"]},"es":{"name":"Enfermedad cerebral de pequeños vasos asociada al gen HTRA1"},"it":{"name":"Malattia dei piccoli vasi cerebrali correlata a HTRA1"},"nl":{"name":"HTRA1-gerelateerde ziekte van cerebrale kleine bloedvaten","synonyms":["HTRA1-gerelateerde cerebrale angiopathie"]},"pt":{"name":"Doença dos pequenos vasos cerebrais HTRA1-relacionada"},"pl":{"name":"Choroba małych naczyń mózgu zależna od HTRA-1","synonyms":["Angiopatia mózgu zależna od HTRA-1"]},"cs":{"name":"HTRA1-vázaná nemoc malých cév mozku","synonyms":["HTRA1-related cerebral angiopathy","HTRA1-vázaná cerebrální angiopatie"]},"uk":{"name":"Захворювання дрібних судин головного мозку, повязане з HTRA1","synonyms":["Церебральна ангіопатія, повязана з HTRA1"]},"zh":{"name":"HTRA1相关大脑小血管疾病","synonyms":["HTRA1相关脑血管病"]},"tr":{"name":"HTRA1-ilişkili serebral küçük damar hastalığı","synonyms":["HTRA1-ilişkili serebral anjiyopati"]}},"xrefs":[{"source":"MONDO","code":"18831","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5680099","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[{"type":"Referred to","orpha":77304,"name":"OBSOLETE: Not NOTCH3-related small vessel disease of the brain","status":"inactive"}],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":477754,"name":"Genetic cerebral small vessel disease","classifications":[156,181]},{"orpha":158124,"name":"Genetic dementia","classifications":[156]},{"orpha":89043,"name":"Rare dementia","classifications":[181]}],"children":[{"orpha":199354,"name":"Cerebral autosomal recessive arteriopathy-subcortical infarcts-leukoencephalopathy","type":"Disease"},{"orpha":482077,"name":"HTRA1-related autosomal dominant cerebral small vessel disease","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}