{"orpha":477754,"name":"Genetic cerebral small vessel disease","type":"Category","group":"Group of disorders","status":"active","flags":[],"synonyms":[],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-477754/","orphanet_url":"https://www.orpha.net/en/disease/detail/477754","names":{"fr":{"name":"Maladie génétique des petites artères cérébrales"},"de":{"name":"Zerebrale Mikroangiopathie, genetisch bedingte"},"es":{"name":"Enfermedad genética de pequeños vasos cerebrales"},"it":{"name":"Malattia cerebrale dei piccoli vasi di origine genetica"},"nl":{"name":"Genetische ziekte van cerebrale kleine bloedvaten"},"pt":{"name":"Doença dos pequenos vasos cerebrais genética"},"pl":{"name":"Genetyczna choroba małych naczyń mózgu"},"cs":{"name":"Geneticky podmíněná nemoc malých cév mozku"},"uk":{"name":"Генетично обумовлене захворювання дрібних судин головного мозку"},"zh":{"name":"遗传性大脑小血管疾病"},"tr":{"name":"Genetik serebral küçük damar hastalığı"}},"xrefs":[{"source":"MONDO","code":"18787","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5681259","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":183503,"name":"Genetic central nervous system and retinal vascular disease","classifications":[156]},{"orpha":71281,"name":"Rare central nervous system and retinal vascular disease","classifications":[181]}],"children":[{"orpha":314572,"name":"Autosomal recessive leukoencephalopathy-ischemic stroke-retinitis pigmentosa syndrome","type":"Disease"},{"orpha":136,"name":"CADASIL","type":"Disease"},{"orpha":575553,"name":"CARASAL","type":"Disease"},{"orpha":477759,"name":"COL4A1 or COL4A2-related cerebral small vessel disease","type":"Category"},{"orpha":313838,"name":"Coats plus syndrome","type":"Disease"},{"orpha":729649,"name":"Early-onset leucoencephalopaty-spasticity-stroke-neurodevelopmental disorder","type":"Disease"},{"orpha":621758,"name":"Fibrosis-neurodegeneration-cerebral angiomatosis syndrome","type":"Disease"},{"orpha":482072,"name":"HTRA1-related cerebral small vessel disease","type":"Clinical group"},{"orpha":85458,"name":"Hereditary cerebral amyloid angiopathy","type":"Disease"},{"orpha":542310,"name":"Leukoencephalopathy with calcifications and cysts","type":"Disease"},{"orpha":728764,"name":"NIT1-related cerebral small vessel disease","type":"Disease"},{"orpha":247691,"name":"Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}