{"orpha":472,"name":"Isosporiasis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Cystoisosporiasis"],"definition":"Isosporiasis (also known as cystoisosporiasis) is an exclusively human parasitosis occurring mainly in the tropics and subtropics, due to infection with <i>Isospora belli</i> (through ingestion of contaminated food), that is frequently asymptomatic or that can cause fever and diarrhea, but that is usually a self-limiting condition in the immunocompetent. HIV-positive individuals are particularly at risk of suffering from symptomatic isosporiasis and can manifest with a more severe clinical course of chronic diarrhea and severe weight loss.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-472/","orphanet_url":"https://www.orpha.net/en/disease/detail/472","names":{"fr":{"name":"Isosporose","definition":"Parasitose strictement humaine survenant principalement dans les régions tropicales et subtropicales, due à une infection par <i>Isospora belli</i> (survenue par ingestion d'aliments contaminés). Elle est souvent asymptomatique mais peut provoquer une fièvre et une diarrhée. Chez les personnes immunocompétentes, il s'agit généralement d'une maladie spontanément résolutive. Les patients séropositifs sont particulièrement exposés au risque de développer une isosporose symptomatique et peuvent présenter une évolution clinique plus sévère avec diarrhée chronique et importante perte de poids."},"de":{"name":"Isosporiasis","synonyms":["Isosporose"],"definition":"Die Isosporiasis (auch bekannt als Cystoisosporiasis) ist eine ausschließlich humane Parasitose, die hauptsächlich in den Tropen und Subtropen auftritt, aufgrund einer Infektion mit <i>Isospora belli</i> (durch Aufnahme kontaminierter Nahrung), die häufig asymptomatisch verläuft oder Fieber und Durchfall verursachen kann. Bei Immunkompetenten ist die Symptomatik normalerweise selbstlimitierend. HIV-positive Personen sind besonders gefährdet, an einer symptomatischen Isosporiase zu erkranken und zeigen oft einen schwereren klinischen Verlauf mit chronischer Diarrhö und starkem Gewichtsverlust."},"es":{"name":"Isosporosis","definition":"Es una parasitosis exclusivamente humana, que se da principalmente en los trópicos y zonas subtropicales, debida a la infección por <i>Isospora belli</i> (mediante la ingesta de comida contaminada). Es con frecuencia asintomática o puede causar fiebre y diarrea, pero en personas inmunocompetentes es, por lo habitual, una condición autolimitada. Los individuos VIH-positivos tienen un mayor riesgo de padecer la isoporiasis sintomática y pueden manifestar un curso clínico grave de diarrea crónica y una pérdida de peso significativa."},"it":{"name":"Isosporiasi","synonyms":["Isosporosi"],"definition":"L'isosporiasi (nota anche come cistoisosporiasi) è una parassitosi esclusivamente umana, presente prevalentemente nelle aree tropicali e subtropicali, causata da un'infezione da Isospora belli (dovuta all'ingestione di cibo contaminato). È spesso asintomatica, ma può anche causare febbre e diarrea; di solito è autolimitante nei soggetti immunocompetenti. I pazienti HIV-positivi sono particolarmente a rischio di sviluppare l'isosporiasi sintomatica e possono presentare un decorso clinico più grave con diarrea cronica e grave perdita di peso."},"nl":{"name":"Isosporiasis","synonyms":["Isosporiase"],"definition":"Isosporiase (ook gekend als cysto-isospriase) is een exclusief humane parasitose die voornamelijk voorkomt in de tropen en subtropen, ten gevolge van infectie met <i>Isospora belli</i> (door ingestie van besmet voedsel). Isosporiase is vaak asymptomatisch of kan koorts en diarree veroorzaken, maar is meestal een zelflimiterende conditie bij immuuncompetente patiënten. Vooral HIV-positieve individuen lopen het risico om aan symptomatische isosporiase te lijden, en kunnen een ernstiger klinisch verloop vertonen met chronische diarree en ernstig gewichtsverlies."},"pt":{"name":"Isosporiose"},"pl":{"name":"Izosporydoza","synonyms":["Cystoisosporiasis"]},"cs":{"name":"Izosporiáza","synonyms":["Cystoizosporiáza"]},"uk":{"name":"Ізоспороз","synonyms":["Цистоізоспороз"],"definition":"Isosporiasis (also known as cystoisosporiasis) is an exclusively human parasitosis occurring mainly in the tropics and subtropics, due to infection with <i>Isospora belli</i> (through ingestion of contaminated food), that is frequently asymptomatic or that can cause fever and diarrhea, but that is usually a self-limiting condition in the immunocompetent. HIV-positive individuals are particularly at risk of suffering from symptomatic isosporiasis and can manifest with a more severe clinical course of chronic diarrhea and severe weight loss."},"zh":{"name":"等孢子球虫病","synonyms":["等孢子球虫病"]},"tr":{"name":"Izosporiaz","synonyms":["Kistoizosporiazis"]}},"xrefs":[{"source":"ICD-10","code":"A07.3","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"1A33","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"137713224"},{"source":"MONDO","code":"0018769","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D021865","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0311386","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"3033","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10023076","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":163588,"name":"Rare parasitic disease","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":null}